“…For CaC0 3 , for all morphologically active sequences, the frequency of the basic amino acids is much enhanced as compared to the expected frequency (see 514). This is surprising since usually, acidic proteins are discussed in CaC03 biomineralization [10] and also in biomimetic mineralization ofCaC03, the usually employed synthetic polymers are anionic [44]. Only a few exceptions with neutral or basic molecules were reported so far for biomineralization [45] or bioinspired mineralization [46,47].…”