Abstract:BackgroundAs of January 15, 2016, secukinumab became the first fully human anti–interleukin-17 monoclonal antibody approved for the treatment of patients with psoriatic arthritis (PsA) in the United States. Secukinumab may be administered with or without loading of 150 mg or 300 mg (patients with concomitant moderate to severe psoriasis only) at weeks 0, 1, 2, 3 and 4 followed by maintenance dosing every 4 weeks. The use of a loading regimen of secukinumab in a real-world setting of patients with PsA has not b… Show more
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