“…Orthopedic implants, in contrast to a transplant which are biological products, are humanmade products. The surface of implants which comes in contact with the live tissues, cells or blood should be essentially made of a biomedical metal such as titanium or titanium alloy for eradication of rejection or infection [2,21,22]. Titanium has acceptable mechanical properties and has been used for orthopedic implants, yet for still better performance titanium is alloyed with small amounts of aluminium and vanadium (Ti-6Al-4V), typically 6% and 4% respectively, by weight [3,23,24].…”