2012
DOI: 10.1159/000338142
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Abstract: Objectives: Despite recent advances in cardiovascular surgery, hyperbilirubinemia after heart valve surgery occurs often and the mechanism is not well clarified. We evaluated the incidence and nature of postoperative hyperbilirubinemia in heart valve surgery patients to analyze its risk factors and to identify its clinical significance for associated morbidity and mortality. Methods: We investigated 334 consecutive patients who underwent heart valve surgery. Postoperative hyperbilirubinemia was defined as tota… Show more

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Cited by 31 publications
(52 citation statements)
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“…[1][2][3]11,12 In this study, all adult cardiac surgery patients with the installation of ECC were included. [1][2][3]11,12 In this study, all adult cardiac surgery patients with the installation of ECC were included.…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…[1][2][3]11,12 In this study, all adult cardiac surgery patients with the installation of ECC were included. [1][2][3]11,12 In this study, all adult cardiac surgery patients with the installation of ECC were included.…”
Section: Discussionmentioning
confidence: 99%
“…2,12 Proportional hazards in Cox regression analysis identified increasing age and presence of diabetes mellitus as independent risk factors for early mortality with an odds ratio of 1.02 and 1.12 (95% confidence interval 1.008-1.029 and 1.02-1.22, respectively) in patients with hyperbilirubinaemia. The in-hospital mortality increased from 4.2% in all patients to 17.4% in those with post-operative hyperbilirubinaemia, which is comparable with reported early mortality between 19% and 25%.…”
Section: Hyperbilirubinaemia After Cardiac Surgerymentioning
confidence: 99%
“…Previous reports have highlighted the importance of either high central venous pressure (CVP) or reduced hepatic perfusion. 8, 12 Scant information is available, however, regarding the relationship between the heart and liver, although liver condition might reflect the severity of heart failure. Recently, a rapid, non-invasive, and reproducible approach was developed to assess liver fibrosis by measuring liver stiffness (LS) using transient elastography.…”
mentioning
confidence: 99%
“…Other risk factors including ejection fraction, increased cardiopulmonary bypass time and use of intra-aortic balloon pump are also important as they have been reported to increase postoperative complications [1]. …”
Section: Resultsmentioning
confidence: 99%