Frequency of Malnutrition in Older Adults: A Multinational Perspective Using the Mini Nutritional Assessment

Kaiser, Matthias J.; Bauer, Jürgen; Rämsch, C.; Uter, Wolfgang; Guigoz, Y.; Cederholm, Tommy; Thomas, David; Anthony, P.; Charlton, Karen E; Maggio, Marcello; Tsai, Alan C.; Vellas, Bruno; Sieber, Cornel

doi:10.1111/j.1532-5415.2010.03016.x

Cited by 778 publications

(552 citation statements)

References 31 publications

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“…1 In Europe about one third of older patients admitted to hospital are malnourished, [2][3][4] which makes it a widespread problem. [2][3][4] The condition is associated with several negative outcomes such as declined functional ability, 5,6 readmissions, and a prolonged length of stay in hospital. 7 Even more critically, a systematic review from 2012 evaluating different nutrition screening tools concludes that there is some evidence that malnutrition is associated with a increased mortality.…”

Section: Introductionmentioning

confidence: 99%

Nutritional status predicts preterm death in older people: A prospective cohort study

et al. 2014

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Section: Introductionmentioning

confidence: 99%

Nutritional status predicts preterm death in older people: A prospective cohort study

et al. 2014

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“…These women were part of the PRIMOS project (PRIMary health care and OSteoporosis) and their baseline 1 MNA scores were reported in 2006 with regard to their bone health. 22 As reported in this earlier study, 92% (n ¼ 323) of the participants were classified as 'well-nourished' and the remaining 8% (n ¼ 28) were found 'at risk of malnutrition'.…”

Section: Materials and Methods Populationmentioning

confidence: 99%

“…1 Disease-related malnutrition have been calculated to carry a cost of about h10.5 billion annually in the United Kingdom alone. 2 Malnutrition has been associated with increased mortality, 3 impaired immune response, reduced muscle and respiratory function, impaired wound healing and longer rehabilitation.…”

Section: Introductionmentioning

confidence: 99%

Mini nutritional assessment and 10-year mortality in free-living elderly women: a prospective cohort study with 10-year follow-up

Lundin

Sääf

et al. 2012

Eur J Clin Nutr

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BACKGROUND/OBJECTIVES: Mini nutritional assessment (MNA) is the most frequently used screening test for malnutrition in elderly populations in continental Europe and Asia. Most studies on MNA's ability to predict mortality have only included persons admitted to hospital, living in nursing homes or at home with professional help with activities of daily living. The aim of this cohort study was to examine if MNA can predict 10-year mortality in the general elderly female population. SUBJECTS/METHODS: Of the 584 free-living elderly women invited, 351 agreed to participate and were tested with MNA between 1999 and 2000. A 10-year follow-up was conducted in 2010 with dates of death obtained from the Swedish death register. RESULTS: Participants whose MNA score was p23.5 points at inclusion had a significantly higher age-adjusted 10-year mortality risk than participants with a MNA score of 423.5 points. The hazard ratio was 2.36 (95% confidence interval 1.25-4.46), P o0.01. CONCLUSIONS: Participants with a MNA score, indicating an increased risk for malnutrition, were more than twice as likely to die during the 10-year follow-up as participants whose MNA score indicated normal nutritional status. Hence, MNA can predict mortality in a general, free-living, elderly female population.

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“…A better understanding of the reasons behind such a paradoxical association is pivotal to help determine target SUA levels for elderly people and other patient groups different from the general population 15, 16. Older adults have age‐related change of appetite regulation and are predisposed to decreased food intake and malnourishment 17, 18. Malnourishment is an independent risk factor for all‐cause and CVD‐related mortality in older people 19.…”

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confidence: 99%

U‐Shaped Association Between Serum Uric Acid Levels With Cardiovascular and All‐Cause Mortality in the Elderly: The Role of Malnourishment

Tseng

Chen

et al. 2018

JAHA

117

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BackgroundThe link between elevated serum uric acid (SUA) levels and cardiovascular disease (CVD)–related mortality in the elderly population remains inconclusive. Nutritional status influences both SUA and CVD outcomes. Therefore, we investigated whether SUA‐predicted mortality and the effect‐modifying roles of malnourishment in older people.Methods and ResultsA longitudinal Taiwanese cohort including 127 771 adults 65 years and older participating in the Taipei City Elderly Health Examination Program from 2001 to 2010 were stratified by 1‐mg/dL increment of SUA. Low SUA (<4 mg/dL) strata was categorized by malnourishment status defined as Geriatric Nutritional Risk Index <98, serum albumin <38 g/L, or body mass index <22 kg/m2. Study outcomes were all‐cause and CVD‐related mortality. Cox models were used to estimate hazard ratios (HRs) of mortality, after adjusting for 20 demographic and comorbid covariates. Over a median follow‐up of 5.8 years, there were 16 439 all‐cause and 3877 CVD‐related deaths. Compared with the reference SUA strata of 4 to <5 mg/dL, all‐cause mortality was significantly higher at SUA <4 mg/dL (HR, 1.16; 95% confidence interval, 1.07–1.25) and ≥8 mg/dL (HR, 1.13; confidence interval, 1.06–1.21), with progressively elevated risks at both extremes. Similarly, increasingly higher CVD‐related mortality was found at the SUA level <4 mg/dL (HR, 1.19; confidence interval, 1.00–1.40) and ≥7 mg/dL (HR, 1.17; confidence interval, 1.04–1.32). Remarkably, among the low SUA (<4 mg/dL) strata, only malnourished participants had greater all‐cause and CVD‐related mortality. This modifying effect of malnourishment remained consistent across subgroups.Conclusions SUA ≥8 or <4 mg/dL independently predicts higher all‐cause and CVD‐related mortality in the elderly, particularly in those with malnourishment.

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Frequency of Malnutrition in Older Adults: A Multinational Perspective Using the Mini Nutritional Assessment

Abstract: The MNA has gained worldwide acceptance and shows a high prevalence of malnutrition in different settings, except for the community. Because of its specific geriatric focus, the MNA should be recommended as the basis for nutritional evaluation in older people.

Cited by 778 publications

References 31 publications

Nutritional status predicts preterm death in older people: A prospective cohort study

Nutritional status predicts preterm death in older people: A prospective cohort study

Mini nutritional assessment and 10-year mortality in free-living elderly women: a prospective cohort study with 10-year follow-up

U‐Shaped Association Between Serum Uric Acid Levels With Cardiovascular and All‐Cause Mortality in the Elderly: The Role of Malnourishment

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