Frequency of Idiopathic Gastric Stasis and Intestinal Transit Disorders in Essential Dyspepsia

Wegener, Martin; Börsch, G; Schaffstein, J; Reuter, Christian; Leverkus, Friedhelm

doi:10.1097/00004836-198904000-00010

Cited by 64 publications

(18 citation statements)

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“…Despite the prevalence of dysmotility-like symptoms, this study showed delayed gastric emptying only in 28% of dyspeptic subjects, which is in agreement with the results of other studies (14,23,24). Delayed gastric emptying has long been considered as the main pathogenetic mechanism underlying functional dyspepsia (10, 25), but two other possible causes have recently been suggested: hypersensitivity to gastric distension and impaired gastric accommodation to a meal (4,6,7).…”

Section: Discussionsupporting

confidence: 91%

Functional Dyspepsia Symptoms, Gastric Emptying and Satiety Provocative Test: Analysis of Relationships

Cuomo

Sarnelli

Grasso

et al. 2001

Scandinavian Journal of Gastroenterology

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Section: Discussionsupporting

confidence: 91%

Functional Dyspepsia Symptoms, Gastric Emptying and Satiety Provocative Test: Analysis of Relationships

Cuomo

Sarnelli

Grasso

et al. 2001

Scandinavian Journal of Gastroenterology

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“…There are many reports demonstrating delayed gastric emptying in patients with FD from both Western55,56 and Asian57-63 countries, and about 40% of FD patients are thought to show delayed gastric emptying after ingestion of solid food 64. However, there are many studies that failed to show a direct connection between delayed gastric emptying and dyspeptic symptoms,65-67 suggesting that the relationship may not be entirely clear.…”

Section: Consensus Statementsmentioning

confidence: 99%

Asian Consensus Report on Functional Dyspepsia

Miwa¹,

Ghoshal²,

Gonlachanvit³

et al. 2012

J Neurogastroenterol Motil

120

138

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Background/AimsEnvironmental factors such as food, lifestyle and prevalence of Helicobacter pylori infection are widely different in Asian countries compared to the West, and physiological functions and genetic factors of Asians may also be different from those of Westerners. Establishing an Asian consensus for functional dyspepsia is crucial in order to attract attention to such data from Asian countries, to articulate the experience and views of Asian experts, and to provide a relevant guide on management of functional dyspepsia for primary care physicians working in Asia.MethodsConsensus team members were selected from Asian experts and consensus development was carried out using a modified Delphi method. Consensus teams collected published papers on functional dyspepsia especially from Asia and developed candidate consensus statements based on the generated clinical questions. At the first face-to-face meeting, each statement was reviewed and e-mail voting was done twice. At the second face-to-face meeting, final voting on each statement was done using keypad voting system. A grade of evidence and a strength of recommendation were applied to each statement according to the method of the GRADE Working Group.ResultsTwenty-nine consensus statements were finalized, including 7 for definition and diagnosis, 5 for epidemiology, 9 for pathophysiology and 8 for management. Algorithms for diagnosis and management of functional dyspepsia were added.ConclusionsThis consensus developed by Asian experts shows distinctive features of functional dyspepsia in Asia and will provide a guide to the diagnosis and management of functional dyspepsia for Asian primary care physicians.

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“…In a meta-analysis of 17 studies involving 868 dyspeptic patients and 397 controls significant delay of solid gastric emptying was present in 3040% of patients with functional dyspepsia [Quartero et al 1998]; however, these findings did not correlate with patient symptoms [Jian et al 1989;Talley et al 1989;Wegener et al 1989]. Results of Figure 1.…”

Section: Gastric Emptying Studiesmentioning

confidence: 99%

Review: Evaluation and management of dyspepsia

Harmon

Peura

2010

Therap Adv Gastroenterol

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Dyspepsia is a common clinical problem seen by both primary care physicians and gastroenterologists. Initial evaluation should focus on the identification and treatment of potential causes of symptoms such as gastroesophageal reflux disease (GERD), peptic ulcer disease, and medication side effects but also on recognizing those at risk for more serious conditions such as gastric cancer. This manuscript discusses the evaluation and management of dyspepsia including the role of proton-pump inhibitors, treatment of Helicobacter pylori, and endoscopy. Finally, treatment of refractory functional dyspepsia is addressed.

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Frequency of Idiopathic Gastric Stasis and Intestinal Transit Disorders in Essential Dyspepsia

Cited by 64 publications

References 0 publications

Functional Dyspepsia Symptoms, Gastric Emptying and Satiety Provocative Test: Analysis of Relationships

Functional Dyspepsia Symptoms, Gastric Emptying and Satiety Provocative Test: Analysis of Relationships

Asian Consensus Report on Functional Dyspepsia

Review: Evaluation and management of dyspepsia

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