Frequency of Erythrocyte Phenotypes in Blood Group Systems ABO and Rhesus at Moba, Province of Tanganyika, Democratic Republic of Congo

Abstract

The determination of blood groups appears to be very useful in transfusion medicine, genetics, forensic medicine, organ transplantation and maternal alloimmunization. In Moba, blood transfusion is indicated in several anemias of the children. The present study aimed to determine the frequency of ABO and Rhesus blood groups in our environment. This is a descriptive cross-sectional study. Blood donors registered at the Moba General Reference Hospital for the period 2015 to 2016 were selected for this study (n = 2292). The Beth-Vincent test was used to determine blood group phenotypes from the monoclonal test sera. Blood groups O (60.5%) and AB (2.5%) were respectively the most frequent and the least encountered. In our series of studies, the numerical frequency order of the phenotypes of the ABO and Rhesus (D) blood groups included in order of importance: O + (n = 1364 or 59.5%); A + (n = 488 or 21.3%); B + (n = 348 or 15.2%); AB + (n = 55 or 2.4%); O − (n = 22 or 1.0%); A − (n = 7 or 0.3%); B − (n = 5 or 0.2%); and AB − (n = 3 or 0.1%). This observed difference between the different ABO and Rhesus groups is significant. Sex does not significantly affect the type of blood group. The distribution of ABO and rhesus groups follows the same Negroid distribution as in many countries. The results should be capitalized for proper priority management of the blood to be stored in the blood bank.

Distribution of ABO and RHD blood group antigens in blood donors in Burkina Faso

“…These results were consistent with those observed in previous study in Madagascar (Randriamanantany et al, ) where allelic frequencies were 0.1558, 0.1987 and 0.6450 respectively for alleles A, B and O. Loua in Guinea, Ndoula in Cameroon and Santovito in Côte d'Ivoire found a predominance of A than allele B (Loua et al, ; Ndoula et al, ; Santovito et al, ). The allele D was most frequent (0.7214); this is consistent with all the studies in African populations, from Central Africa to Maghreb and from West to East (Hamed et al, ; Kabemba et al, ; Mohammed et al, ; Tesfaye, Petros, & Andargie, ).…”

“…These results were also similar to those in other West African countries (Table ) as in Guinea (O = 0.4888, B = 0.2386; A = 0.2254; AB = 0.0472), Nigeria (O = 0.529, B = 0.231; A = 0.213; AB = 0.27) and Côte d'Ivoire (O = 0.551, B = 0.225; A = 0.17; AB = 0.054) (Iyiola et al, ; Loua et al, ; Santovito et al, ). However, they were not consistent with those in Central Africa and Maghreb where the sequence was O > A> B > AB (Benahadi et al, ; Kabemba et al, ; Ndoula, Noubiap, Nansseu, & Wonkam, ; Said et al, ; SmailChadli et al, ). The phenotypes RHD+ were predominant in our study, as in the other studies across the different African regions.…”

Blood Group Cartography (ABO, RHESUS, KELL and DUFFY) and Hemogram of Icteric Newborn in Sendwe Hospital, Lubumbashi/D.R.C

“…For Rhesus group D, the percentage of our negative RhD births is 4 times higher than the region rate and is double the known averages for the black race (Table 9) [19,39,45].…”