Frequency and Clinical Manifestations of Dengue in Urban Medellin, Colombia

Restrepo, Berta Nelly; Beatty, Mark E.; Góez, Yenny; Ramírez, Ruth; Letson, G. William; Díaz, Francisco Javier; Piedrahita, Leidy Diana; Osorio, Jorge E.

doi:10.1155/2014/872608

Cited by 20 publications

(34 citation statements)

References 20 publications

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“…Only 6.6% of cases were found in older age group >50 years. This finding is similar with Nelly B et al 8 In their study male predominance (93.4% cases) and only 6.6% female cases were observed. This finding does not correlate with study done by Yousufetal Md, et al 9 This gender disparity may be due to lack of penetration and lack of health awareness among females.…”

Section: Resultssupporting

confidence: 92%

“…Similar presentation was seen in Nelly B et al, but in 17.9% cases. 8 Multi organ failure cases were absent in our study. These findings were observed in 0.66% of cases in Yousuf Md et al, study.…”

contrasting

confidence: 48%

“…8,9,2 Rash was seen in 10.4% cases, similarly Nelly B et al noticed rash in 9.6%, whereas Deshwal et al, observed rash in 37.86%. 8,2 In present study, 54 (50.9%) patients were having normal heart rate, 5 (4.7%) patients were having bradycardia and 47 (44.3%) were having tachycardia. Whereas Deshwal et al, observed bradycardia in 8.3% cases and Yousuf Md, et al noticed in 11.33%.…”

mentioning

confidence: 84%

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Clinico-laboratory profile of dengue patients in a tertiary hospital of Eastern India

Murmu¹,

Singh²,

Kamble³

et al. 2018

Int J Res Med Sci

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INTRODUCTIONDengue is the most rapidly spreading mosquito-borne viral disease of mankind, with a 30 fold increase in global incidence over the last 5 decades. It is a major public health concern throughout the tropical and subtropical regions of the world.Almost half of the world's population lives in countries where dengue is endemic. According to WHO, about 50-100 million dengue infections are estimated to occur annually in more than 100 endemic countries. ABSTRACTBackground: Dengue is the most rapidly spreading mosquito-borne viral disease of mankind. According to WHO, about 50-100 million new dengue infections are estimated to occur annually in more than 100 endemic countries. So, the present study has been done to analyzed varied clinical and laboratory profile of confirm dengue cases. Methods: Cross-sectional observational study was undertaken among 106 adult Ig M Ab positive cases admitted during October 2015 to September 2017. All patients were evaluated clinically and subjected for relevant laboratory investigations.Results: In our study male and female ratio was 20.2:1. Most common symptom was fever (95.3%) and least common was jaundice. Second most symptom was headache (70.8%). Myalgia was present in 49.1% of cases. 54.7% had nausea/vomiting. Hypotension was noticed in 33% of cases whereas encephalopathy and melaena was found in 6.6% and 2.83% respectively. Leucopenia was present in 57.5% and thrombocytopenia in 50.9% of cases. Conclusions: Younger male were commonly affected with dengue fever and promptly responded to conservative therapy due to early confirmation of diagnosis. Mortality was only 1.8% cases, may be due to delay in seeking medical attention.

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Section: Resultssupporting

confidence: 92%

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confidence: 48%

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confidence: 84%

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Clinico-laboratory profile of dengue patients in a tertiary hospital of Eastern India

Murmu¹,

Singh²,

Kamble³

et al. 2018

Int J Res Med Sci

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“…In this study there was no significant difference between the sexes or ethnic groups in DENV prevalence, as described previously in other settings 4, 16, 26, 32, 36. However, the seroconversion rate seemed to be increased in Afro-Colombians compared to whites.…”

Section: Discussionsupporting

confidence: 81%

Dengue virus serological prevalence and seroconversion rates in children and adults in Medellin, Colombia: implications for vaccine introduction

Carabalí

Lim

Velez

et al. 2017

International Journal of Infectious Diseases

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“…La primera etapa se caracteriza por fiebre de 2 a 7 días de duración asociada a síntomas inespecí-ficos tales como: cefalea, dolor retroocular, artralgias, mialgias, puede aparecer exantema o eritema facial. Posteriormente, con la defervescencia se inicia la etapa crítica, dada por la extravasación de plasma a tejidos, cuya manifestación más grave puede ser el choque 27 . En esta etapa se debe evaluar al paciente y buscar signos de alarma (ver tabla 2).…”

Section: Dengueunclassified

Enfoque clínico del síndrome febril agudo en Colombia

Cortés

Romero-Moreno

Aguirre-León

et al. 2017

Infect

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ResumenEl síndrome febril agudo se refiere a un conjunto de enfermedades que cursan con fiebre en el contexto de exposición en áreas tropicales y que constituyen un motivo de consulta frecuente en el servicio de urgencias. Este artículo revisa el enfoque clínico del síndrome febril agudo en Colombia y de las enfermedades más prevalentes o graves que lo causan. Se presenta el enfoque sindromático y se establece una revisión sucinta de los síntomas principales, signos de alarma, tratamiento, prevención y notificación en el sistema de vigilancia en salud pública.Palabras clave: Síndrome febril agudo; Malaria; Dengue; Virus chikungunya; Hepatitis; Fiebre amarilla; Infecciones por rickettsia; Leptospirosis; Absceso hepático; Fiebre hemorrágica ébola Clinical approach to acute febrile syndome in Colombia AbstractAcute febrile syndrome refers to a group of diseases with fever as a main symptom, in a context of living in or having been exposed to tropical climates. It is a frequent cause for consultation in the emergency room. This paper reviews the clinical approach to acute febrile syndrome and the most prevalent or severe causes. We present the syndromatic approach to the patient and a short review of the main symptoms, alarm signs, treatment, prevention and notification to the public health surveillance system of the most frequent causes.Keywords: Acute febrile syndrome; Malaria; Dengue; Chikungunya virus; Hepatitis; Yellow fever; Rickettsia infections; Leptospirosis; Liver abscess; Hemorrhagic fever ebola IntroducciónColombia es un país ubicado en el trópico y endémico para distintas enfermedades febriles agudas de origen infeccioso, de las cuales, en el caso de malaria se puede realizar un diagnóstico oportuno y rápido, no así en las otras causas de sín-drome febril no palúdico, por lo que quedan sin diagnóstico etiológico claro. A pesar del intento de la OMS por generar algoritmos diagnósticos y terapéuticos en la enfermedad febril aguda, todavía existe mucha confusión acerca del enfoque y manejo del paciente con fiebre sin foco aparente en el servicio de urgencias y, más aún, en su seguimiento hospitalario e incluso ambulatorio 1-3 .Se define síndrome febril agudo (SFA) como el estado mór-bido con inicio repentino de fiebre, de menos de 7 días de evolución, en pacientes entre 5 y 65 años, en los cuales no se hayan identificado signos ni síntomas relacionados con un foco infeccioso aparente 4 . Actualmente, en Colombia existen más de 60 enfermedades infectocontagiosas consideradas de interés en salud pública, con un comportamiento endemoepidémico en más del 85% del territorio nacional, que se manifiestan a través de SFA 5 . Debido a la diversidad de enfermedades causantes y a la posibilidad de que el cuadro corresponda a un caso de malaria, dengue, rickettiosis u otras enfermedades potencialmente letales y de importancia en salud pública, es muy importante para el médico colombiano tener la capacidad de abordar los casos para garantizar una atención apropiada y una selección de las pruebas diagnósticas apropiadas...

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Frequency and Clinical Manifestations of Dengue in Urban Medellin, Colombia

Cited by 20 publications

References 20 publications

Clinico-laboratory profile of dengue patients in a tertiary hospital of Eastern India

Clinico-laboratory profile of dengue patients in a tertiary hospital of Eastern India

Dengue virus serological prevalence and seroconversion rates in children and adults in Medellin, Colombia: implications for vaccine introduction

Enfoque clínico del síndrome febril agudo en Colombia

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