French Registry on Acute ST-elevation and non ST-elevation Myocardial Infarction 2010. FAST-MI 2010

Hanssen, M.; Cottin, Yves; Khalife, Khalifé; Hammer, Laure; Goldstein, Patrick; Puymirat, Étienne; Mulak, Geneviève; Drouet, Élodie; Pace, Benoît; Schultz, Eric H.; Bataille, Vincent; Ferrières, Jean; Simon, Tabassome; Danchin, Nicolás; investigators, Fast-Mi

doi:10.1136/heartjnl-2012-301700

Cited by 152 publications

(105 citation statements)

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“…Cardiogenic shock is a common complication of severe myocardial infarction. As in the FAST-MI registry [18], the frequency of cardiogenic shock was 4% in the general population of MI, similar to the rate found in our study 4.39%. It is a predictor of early and late mortality.…”

Section: Discussionsupporting

confidence: 78%

Prevalence and Management of Acute Coronary Syndrome with Persistent ST-Segment Elevation in Cardiology Unit of General Hospital of Grand Yoff in Dakar (Experience a Single Center)

Dioum¹,

Mbaye²,

Ngaïdé³

et al. 2017

J Cardiovasc Dis Diagn

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Section: Discussionsupporting

confidence: 78%

Prevalence and Management of Acute Coronary Syndrome with Persistent ST-Segment Elevation in Cardiology Unit of General Hospital of Grand Yoff in Dakar (Experience a Single Center)

Dioum¹,

Mbaye²,

Ngaïdé³

et al. 2017

J Cardiovasc Dis Diagn

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“…The results of the CAPTIM (Comparison of Primary Angioplasty and Pre‐hospital Fibrinolysis in Acute Myocardial Infarction) study indicated that prehospital fibrinolysis, particularly in the first 2 hours after symptoms onset, can be more effective than transfer for primary PCI 20. In fact, 2 major registries—the Vienna STEMI Registry21 and the French Registry on Acute ST‐Elevation and Non‐ST‐elevation Myocardial Infarction (FAST‐MI) 201022—showed similar results for patients treated at an early stage.…”

Section: Discussionmentioning

confidence: 99%

Implementation of a Regional Network for ST‐Segment–Elevation Myocardial Infarction (STEMI) Care and 30‐Day Mortality in a Low‐ to Middle‐Income City in Brazil: Findings From Salvador's STEMI Registry (RESISST)

Filho

Solla³

et al. 2018

JAHA

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BackgroundFew data exist on regional systems of care for the treatment of ST‐segment–elevation myocardial infarction (STEMI) in developing countries. Our objective was to describe temporal trends in 30‐day mortality and identify predictors of mortality among STEMI patients enrolled in a prospective registry in Brazil.Methods and ResultsFrom January 2011 to June 2013, 520 patients who received initial STEMI care at 23 nonspecialized public health units or hospitals, some of whom were transferred to a public cardiology referral center, were identified through a regional STEMI network supported by telemedicine and the local prehospital emergency medical service. We stratified patients into five 6‐month periods based on presentation date. Mean age (±SD) of patients was 62.0 (±12.2) years, and 55.6% were men. The mean Global Registry of Acute Coronary Events (GRACE) score was 145 (±34). Overall mortality at 30 days was 15.0%. Use of dual antiplatelet therapy and statins increased significantly from baseline (January 2011) to period 5 (June 2013): 61.8% to 93.6% (P<0.001) and 60.4% to 79.7% (P<0.001), respectively. Rates of primary reperfusion also increased (29.1%–53.8%; P<0.001), and more patients were transferred to the referral center (44.7%–76.3%; P=0.001). Thirty‐day mortality rates decreased from 19.8% to 5.1% (P<0.001). In multivariable analysis, factors independently associated with 30‐day mortality were higher GRACE score, history of previous stroke, lack of transfer to the referral center, and lack of use of optimized medical therapy.ConclusionsImplementation of a regional STEMI system was associated with lower mortality and higher use of evidence‐based therapies.

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“…Heart failure 100 (16) 65 (14) 117 (8) 105 (8) 148 (8) <0.001 PAD 73 (12) 70 (15) 197 (14) 161 (12) 190 (10) In patients with NSTEMI, mortality decreased from 17.2% to 6.3%, and adjusted HR decreased to 0. …”

Section: Discussionmentioning

confidence: 99%

“…Five nationwide French registries were conducted 5 years apart over a 20-year period : USIK 1995, 13 USIC (Unité de Soins Intensifs Coronaires) 2000, 14 FAST-MI (French Registry of Acute ST-Elevation or non-ST-elevation Myocardial Infarction) 2005 (NCT00673036), 15 FAST-MI 2010 (NCT01237418), 16 and FAST-MI 2015 (NCT02566200) 17 (Methods I in the online-only Data Supplement). The methods used for these registries have been detailed previously .…”

Section: Patient Populationmentioning

confidence: 99%

Acute Myocardial Infarction

et al. 2017

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BACKGROUND: ST-segment-elevation myocardial infarction (STEMI) and non-ST-segment-elevation myocardial infarction (NSTEMI) management has evolved considerably over the past 2 decades. Little information on mortality trends in the most recent years is available. We assessed trends in characteristics, treatments, and outcomes for acute myocardial infarction in France between 1995 and 2015. METHODS:We used data from 5 one-month registries, conducted 5 years apart, from 1995 to 2015, including 14 423 patients with acute myocardial infarction (59% STEMI) admitted to cardiac intensive care units in metropolitan France. RESULTS:From 1995 to 2015, mean age decreased from 66±14 to 63±14 years in patients with STEMI; it remained stable (68±14 years) in patients with NSTEMI, whereas diabetes mellitus, obesity, and hypertension increased. At the acute stage, intended primary percutaneous coronary intervention increased from 12% (1995) to 76% (2015) in patients with STEMI. In patients with NSTEMI, percutaneous coronary intervention ≤72 hours from admission increased from 9% (1995) to 60% (2015). Six-month mortality consistently decreased in patients with STEMI from 17.2% in 1995 to 6.9% in 2010 and 5.3% in 2015; it decreased from 17.2% to 6.9% in 2010 and 6.3% in 2015 in patients with NSTEMI. Mortality still decreased after 2010 in patients with STEMI without reperfusion therapy, whereas no further mortality gain was found in patients with STEMI with reperfusion therapy or in patients with NSTEMI, whether or not they were treated with percutaneous coronary intervention. CONCLUSIONS:Over the past 20 years, 6-month mortality after acute myocardial infarction has decreased considerably for patients with STEMI and NSTEMI. Mortality figures continued to decline in patients with STEMI until 2015, whereas mortality in patients with NSTEMI appears stable since 2010. ORIGINAL RESEARCH ARTICLE T he early outcome of patients with acute myocardial infarction (AMI) has improved considerably. Acute Myocardial Infarction1-6 Among patients with AMI, however, the pathophysiology, management, and outcomes differ between those with ST-segment-elevation myocardial infarction (STEMI) and non-ST-segment-elevation myocardial infarction (NSTEMI). Traditionally, patients with NSTEMI have a substantially lower early mortality than those with STEMI, but a higher risk of long-term mortality, likely explained by more frequent risk factors and comorbidities, and a greater burden of coronary artery disease. 7-9The improvement in early outcomes up to the early 2010s has been attributed to changes in patient populations, more frequent use of revascularization procedures, and increased use of recommended medications. 5,6,[10][11][12] Since 2010, however, little information is available on early outcomes in real-world settings, although the use of percutaneous coronary interventions (PCIs) has continued to increase and newer antithrombotic agents have become available and are now widely used. Whether these changes in the most recent years have translated ...

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French Registry on Acute ST-elevation and non ST-elevation Myocardial Infarction 2010. FAST-MI 2010

Cited by 152 publications

References 15 publications

Prevalence and Management of Acute Coronary Syndrome with Persistent ST-Segment Elevation in Cardiology Unit of General Hospital of Grand Yoff in Dakar (Experience a Single Center)

Prevalence and Management of Acute Coronary Syndrome with Persistent ST-Segment Elevation in Cardiology Unit of General Hospital of Grand Yoff in Dakar (Experience a Single Center)

Implementation of a Regional Network for ST‐Segment–Elevation Myocardial Infarction (STEMI) Care and 30‐Day Mortality in a Low‐ to Middle‐Income City in Brazil: Findings From Salvador's STEMI Registry (RESISST)

Acute Myocardial Infarction

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