Phytochemicals - Source of Antioxidants and Role in Disease Prevention 2018
DOI: 10.5772/intechopen.76719
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Abstract: Free radicals or reactive oxygen species (ROS) generated from various sources in the environment as well as from cellular processes in the body are of serious health challenges. Overwhelming levels of these free radicals disrupt the antioxidant defense system in the body thereby damaging cell membranes and cellular macromolecules such as proteins, lipids and nucleic acids leading to cell death or causing mutations leading to uncontrolled cell division. Once the cellular antioxidant system is disrupted and beco… Show more

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Cited by 101 publications
(72 citation statements)
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“…e phytochemicals in SAHA extracts prevent lipid peroxidation by binding to lipid peroxides. Our findings are in agreement with previously reported results by other workers [40,41].…”
Section: Evidence-based Complementary and Alternative Medicinesupporting
confidence: 94%
“…e phytochemicals in SAHA extracts prevent lipid peroxidation by binding to lipid peroxides. Our findings are in agreement with previously reported results by other workers [40,41].…”
Section: Evidence-based Complementary and Alternative Medicinesupporting
confidence: 94%
“…Regarding the precision of the method, it was determined in terms of the intra-day and inter-day precision in three different concentration levels (5,15, and 25 µg/mL). Intra-day precision was assessed by the application of the developed methodology on the same day, by the same analyst (experimental replicates n = 6), while inter-day precision was evaluated with a similar procedure on different days (n = 18).…”
Section: Analytical Methods Validationmentioning
confidence: 99%
“…Lipid peroxyl radicals can become lipid hydroperoxides which can then be decomposed into aldehydes or form cyclic, isoprotan, and hydrocarbon endoperoxides. The third stage is the chain breaking occurs after the interaction of one ROO with other radicals or antioxidants (Engwa, 2018). Lipid peroxidation produces oxidation products.…”
Section: Resultsmentioning
confidence: 99%