Free adipose tissue (FAT) graft pooling for severe dead space management

Abstract

Complex lower extremity trauma with large soft tissue defects requires early wound coverage to reduce the risk of complications. In particular circumstances, however, local or free flaps may be contraindicated due to local or systemic issues. This study presents a helpful and effective salvage procedure for soft tissue reconstruction that uses autologous fat grafting combined with negative pressure wound therapy. Level of Evidence V; Therapeutic Studies; Expert Opinion.

A Large Defect of the Upper Arm and Elbow Exposing Humerus Bone

“…Autologous fat grafting techniques have been used to improve wound healing in cases of exposed bone. 3 Adipose-derived stem cells have been shown to increase growth factors, primarily vascular endothelial growth factor and fibroblast growth factor. 4 In the present conundrum, an autologous fat graft was selected to replace the dead space of the surgical defect.…”