2017
DOI: 10.1016/j.metabol.2016.12.005
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Frailty and nutrition: From epidemiological and clinical evidence to potential mechanisms

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Cited by 122 publications
(113 citation statements)
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References 74 publications
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“…Nutrition provides energy and essential nutrients and helps the human body to function properly and maintain homeostasis. The nutrients found in observational and intervention studies to show promising results in relation to frailty are protein and some selected micronutrients, such as carotenoids and vitamins . Although evidence on individual nutrients or food items is important, when the food is consumed, various micro‐ and macronutrients interact with each other, and may cause synergistic effects.…”
mentioning
confidence: 99%
See 1 more Smart Citation
“…Nutrition provides energy and essential nutrients and helps the human body to function properly and maintain homeostasis. The nutrients found in observational and intervention studies to show promising results in relation to frailty are protein and some selected micronutrients, such as carotenoids and vitamins . Although evidence on individual nutrients or food items is important, when the food is consumed, various micro‐ and macronutrients interact with each other, and may cause synergistic effects.…”
mentioning
confidence: 99%
“…This diet is low in saturated fat and has been associated with multiple health benefits, including lower incidence of cardiovascular disease, neurodegenerative diseases, diabetes, and overall cancer, as well as longer survival . Only a few studies have examined associations between the Mediterranean diet and frailty risk, and the results have been mixed and inconclusive . Furthermore, to our knowledge, no meta‐analysis has been performed.…”
mentioning
confidence: 99%
“…An inadequate protein intake, which is very common among the elderly, accelerates the progression of sarcopenia. [170]. Older people very often reduce the consumption of animal proteins due to difficulty in chewing due to edentulism and the reduction of the perception of taste and smell due to polypharmacy.…”
Section: Conclusion Remarks On Nutrition and Frailtymentioning
confidence: 99%
“…Jednak nawet jeśli spożycie białka jest wystarczające, to istnieje wiele czynników związanych z wiekiem (oporność na insulinę, zaburzenia trawienia białka i wchłanianie aminokwasów), które mogą hamować stymulację syntezy białek mięśniowych u osób starszych. Ta niska synteza białek mięśniowych w połączeniu z wysoką częstością rozpadu obserwowaną u osób starszych powoduje ujemny bilans białka mięśniowego i wpływa negatywnie na masę mięśni szkieletowych [23].…”
Section: Zapobieganie Zespołowi Kruchości I Jego Leczenieunclassified
“…Uzasadnieniem dla tego zjawiska jest udokumentowana przewaga procesów katabolicznych nad anabolicznymi u osób starszych [14]. Odżywianie jest czynnikiem ściśle związanym z FS [23]. Powszechnie zaakceptowane kryteria kruchości dotyczące słabości, niezamierzonej utraty masy ciała, niskiej siły mięśni, uczucia wyczerpania, zmniejszenia aktywności fizycznej i powolnego tempa poruszania się są mniej lub bardziej powiązane ze złymi nawykami żywieniowymi.…”
Section: Zapobieganie Zespołowi Kruchości I Jego Leczenieunclassified