2017
DOI: 10.18632/aging.101162
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Abstract: We examined the associations between frailty and inflammatory markers, in particular neutrophil lymphocyte ratio (NLR), in elderly cancer patients. We conducted cross-sectional analyses of data derived from the Carolina Seniors Registry (CSR), a database of geriatric assessments (GA) in older adults (≧65 years) with cancer. We included patients in the CSR who had a GA and complete blood count test before initiation of therapy. The primary outcome was frailty, determined using the 36-item Carolina Frailty Index… Show more

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Cited by 34 publications
(31 citation statements)
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References 47 publications
(64 reference statements)
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“…In addition, frailty is also one of the important parameters of cancers [ 29 , 30 ]. A recent study reported the association between frailty and inflammatory markers in elderly cancer patients [ 31 ]. Our previous study suggested that renal function has potential to predict postoperative frailty [ 32 ].…”
Section: Discussionmentioning
confidence: 99%
“…In addition, frailty is also one of the important parameters of cancers [ 29 , 30 ]. A recent study reported the association between frailty and inflammatory markers in elderly cancer patients [ 31 ]. Our previous study suggested that renal function has potential to predict postoperative frailty [ 32 ].…”
Section: Discussionmentioning
confidence: 99%
“…Compared with healthy people, the NLR is higher in patients with rheumatoid arthritis, Behçet’s disease, ankylosing spondylitis [ 15 ]. An increased NLR was recently shown to be associated with the incidence of frailty and survival outcomes in cancer patients [ 16 ].…”
Section: Introductionmentioning
confidence: 99%
“…The NLR and RDW, as easily detected, highly reproducible, and low-cost inflammatory markers, reflect the status of inflammatory diseases; however, few studies have determined the relationship between frailty, and the NLR and RDW [ 16 , 22 ]. Indeed, this relationship in patients with CHD has not been investigated.…”
Section: Introductionmentioning
confidence: 99%
“…In addition, frailty is also an important aspect of cancer burden [ 30 , 31 ]. A recent study reported an association between frailty and inflammatory markers in elderly cancer patients [ 32 ]. Our previous study suggested that renal function has utility in predicting postoperative frailty [ 33 ].…”
Section: Discussionmentioning
confidence: 99%