Fragmentation hemolysis in a patient with hypertrophic obstructive cardiomyopathy and mitral valve prolapse.

Maeda, Takeshi; Ashie, Takeshi; Kikuiri, Kuniyasu; Fukuyama, Shuzaburo; Yamaguchi, Y; Yoshida, Erio; Shimamoto, Kazuaki; Ito, Osamu

doi:10.1253/jcj.56.970

Cited by 8 publications

(8 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…2 Maeda et al reported a 65-yearold female with hemolysis associated with streptococcal endocarditis of the mitral valve. 3 That patient had an underlying obstructive hypertrophic cardiomyopathy with a high pressure gradient in the left ventricular outflow tract and a moderate mitral regurgitation due to mitral valve prolapse. The infection improved after antibiotic treatment, but the hemolysis persisted.…”

Section: Discussionmentioning

confidence: 99%

Hemolytic anemia in native valve infective endocarditis: a rare case report and review of literature.

Manju¹

2020

ijmhs

View full text Add to dashboard Cite

Hemolytic anemia (HA) is not a common presentation in infectiousendocarditis (IE) and has only been reported in very few cases. Althoughdiseased valves may cause shearing stress that fragments RBCs, similar to thatassociated with mechanical heart valves, an autoimmune hemolytic process hasalso been implicated. We reported a case of patient who had HA secondary toacute IE due to MRSA. The anemia completely resolved after treating the (IE) .The cause was most likely mechanical shearing (schistocytes or fragmentedRBCs present on peripheral smear) by the large vegetation on native valve ;autoimmune hemolysis was considered unlikely in this case due to consistently negative Coombs tests and failure to respond to corticosteroids.

show abstract

Section: Discussionmentioning

confidence: 99%

Hemolytic anemia in native valve infective endocarditis: a rare case report and review of literature.

Manju¹

2020

ijmhs

View full text Add to dashboard Cite

show abstract

“…Both mechanical hemolysis and autoimmune hemolysis have been described 2, 3, 4. Hsuan‐Li et al reviewed six cases of hemolytic anemia secondary to endocarditis; in all the cases, there was the presence of fragmented erythrocytes suggestive of intravascular hemolysis 5.…”

Section: Discussion and Review Of Literaturementioning

confidence: 99%

“…Bacterial endocarditis associated with anemia is a rare presentation and has only been reported in a few case studies, and the mechanisms were postulated to be hemolytic anemia with normochromic and normocytic cells. Both mechanical hemolysis and autoimmune hemolysis have been described . Hsuan‐Li et al reviewed six cases of hemolytic anemia secondary to endocarditis; in all the cases, there was the presence of fragmented erythrocytes suggestive of intravascular hemolysis .…”

Section: Discussion and Review Of Literaturementioning

confidence: 99%

Hemolytic anemia due to native valve subacute endocarditis with Actinomyces israelii infection

Toom

2018

Clinical Case Reports

View full text Add to dashboard Cite

show abstract

“…LVOT obstruction presenting as hemolytic anemia has been associated with obstructive HCM in only a few case reports [12][13][14][15][16][17] ; it is more notably associated with prosthetic valves. 18 These case reports proposed that gradients >50 mm Hg may create significant shear stress, causing red blood cell fragmentation and subsequent hemolysis.…”

Section: Discussionmentioning

confidence: 99%

Are Zebras Simply Striped Horses?

et al. 2016

View full text Add to dashboard Cite

ForewordInformation about a real patient is presented in stages (boldface type) to experts (Drs Olson, Michelena, and Gersh) Two weeks earlier, he presented to a regional hospital with persistent cough, progressive dyspnea, orthostasis, and new low-volume hemoptysis. On admission to the outside hospital, the patient was hypoxic and urgently intubated after he failed to respond to noninvasive positive pressure ventilation. A bronchoscopy demonstrated blood within the airways. Bronchoalveolar lavage (BAL) revealed a bloody return containing a large percentage of hemosiderin-laden macrophages. Cytology and cultures of the BAL were negative for infection or malignancy. He was extubated but continued to have intermittent bouts of dyspnea, hypoxia, and bilateral alveolar infiltrates on chest imaging. Therefore, a right lung lower-lobe wedge biopsy was performed. The biopsy specimen was not immediately available for review at the time of transfer but was interpreted elsewhere as demonstrating hemosiderosis without capillaritis. A systolic murmur prompted a transthoracic echocardiogram (TTE), which reported obstructive HCM.

show abstract

Fragmentation hemolysis in a patient with hypertrophic obstructive cardiomyopathy and mitral valve prolapse.

Cited by 8 publications

References 8 publications

Hemolytic anemia in native valve infective endocarditis: a rare case report and review of literature.

Hemolytic anemia in native valve infective endocarditis: a rare case report and review of literature.

Hemolytic anemia due to native valve subacute endocarditis with Actinomyces israelii infection

Are Zebras Simply Striped Horses?

Contact Info

Product

Resources

About