Journal of Chromatography A 2012 DOI: 10.1016/j.chroma.2011.12.094 View full text
Ming-Tsai Liang, Ru-Chien Liang

Abstract: In this study, a three-section simulated moving bed (SMB) with an open-loop design is used to fractionate polyethylene glycol (PEG) with different molecular weights. The purchased PEGs are mixed and separated by the open-loop SMB. A size-exclusion column with a pore size ranging from 10 to 100 nm, TOSOH GMPW 7.5 mm × 30 cm, is used to separate the mixtures. Based on the Triangle theory, the operating parameters of the SMB are determined and used to separate the three binary mixtures. The results show that the …

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