2018
DOI: 10.18632/aging.101388
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Abstract: Previous studies have showed the associations between various BRCA1-interacting protein 1 (BRIP1) polymorphisms and cancer risk. But, these results were inconsistent. This meta-analysis based on 18 studies involving 13,716 cancer patients and 15,590 cancer-free controls is aimed at to evaluate the relationship between the four common SNPs of BRIP1 (rs2048718, rs4988344, rs4986764, and rs6504074) and cancer risk. The results showed a decreased risk of rs2048718 or rs4986764 for cervical cancer rather than breas… Show more

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Cited by 4 publications
(2 citation statements)
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References 27 publications
(31 reference statements)
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“… Age at diagnosis CG (2.7%) -0.99 101.43 0.868 0.96-1.0 CA (27.9%) -0.99 101.43 0.868 0.96-1.0 GC (69.5%) rs4986764 rs4986765 1 56.42 0.526 0.96-1.0 rs4986764 ( Ma et al , 2013 ; Ren et al , 2013 ; Shi et al , 2013 ; Oussalah et al. , 2017 ; Liu et al , 2018 ) rs4986765 ( Oussalah et al , 2017 ) AC (11.7%) 1 56.42 0.526 0.96-1.0 AT (18.8%) 1 56.42 0.526 0.96-1.0 19p13 XRCC1 CTGC (33.5%) rs25487 rs25486 rs1799782 rs762507 -0.97 104.68 0.879 0.94-1.0 rs25487 ( Roberts et al , 2011 ; Jin et al , 2015 ; Zhu et a...…”
Section: Resultsmentioning
confidence: 99%
“… Age at diagnosis CG (2.7%) -0.99 101.43 0.868 0.96-1.0 CA (27.9%) -0.99 101.43 0.868 0.96-1.0 GC (69.5%) rs4986764 rs4986765 1 56.42 0.526 0.96-1.0 rs4986764 ( Ma et al , 2013 ; Ren et al , 2013 ; Shi et al , 2013 ; Oussalah et al. , 2017 ; Liu et al , 2018 ) rs4986765 ( Oussalah et al , 2017 ) AC (11.7%) 1 56.42 0.526 0.96-1.0 AT (18.8%) 1 56.42 0.526 0.96-1.0 19p13 XRCC1 CTGC (33.5%) rs25487 rs25486 rs1799782 rs762507 -0.97 104.68 0.879 0.94-1.0 rs25487 ( Roberts et al , 2011 ; Jin et al , 2015 ; Zhu et a...…”
Section: Resultsmentioning
confidence: 99%
“…Another variant, rs4986764 of BRIP1 was explored in the studied population and the same variant was found in multiple cancers like non-small-cell lung cancer, cervical cancer, breast cancer, and hepatocellular carcinoma, where it was found to be associated with the higher risk. [26][27][28][29][30] In another study from the Korean population, it was observed that BRIP1 shows a significant association with ovarian and breast cancer. [31] Our study also poses that the variant rs4986764 of BRIP1 also shows a significant association with our population.…”
Section: Brip1mentioning
confidence: 99%