Förster resonance energy transfer (FRET) and applications thereof

Abstract

FRET is a nonradiative process of energy transfer that is based on the dipole–dipole interactions between molecules that are fluorescent.

Fatty acids may influence insulin dynamics through modulation of albumin‐Zn2+ interactions

“…FRET is based on the dipole-dipole interaction between two fluorescent molecules and involves the transfer of excitation energy upon absorption of light from a donor molecule to an acceptor molecule in close proximity. [71] Because the efficiency of energy transfer depends on the inverse of the 6 th power of the distance, FRET has been used as a molecular ruler to measure nanometer size distances between 10-80 Å in biomolecules and to study the association of interacting partners in multi-subunit complexes (Figure 2A; [72] ). T6 hexameric insulin has a size of around 40 Å which is well within the distance range that can be measured by FRET.…”

Recent Advances in Ternary Organic Solar Cells Based on Förster Resonance Energy Transfer

“…The molecular processes involved in FRET could be summarized as follows. [ 54–57 ] First, the energy absorption of donor molecule (normally a fluorophore) leads to its excitement from the ground state to the excited singlet state. The donor molecule features many excited states, in which vibrational relaxation to excited singlet state through internal conversion is very fast, and consequently the emission from this state occurs easily.…”

Bicolour fluorescent molecular sensors for cations: design and experimental validation

“…A related phenomenon in which the emission involves an interaction between two fluorophores (Figure 5A) is the Förster resonance energy transfer (FRET). [53][54][55] This process consists of a non-radiative excitation transfer 56 from the excited donating (D*) group to the acceptor group (A) in its ground state (Figure 5B). This latter group relaxes via a A*(S1) → A(S0) process thus emitting in a different wavelength (Figure 5C).…”

“…5A ) is the Förster resonance energy transfer (FRET). 53–55 This process consists of a non-radiative excitation transfer 56 from the excited donating (D*) group to the acceptor group (A) in its ground state ( Fig. 5B ).…”