Formation of Milia Following Abrasive Treatment for Postacne Scarring

Multiple milia due to radiotherapy

“…6,8,9 They may be seen connected by a cord of undifferentiated epithelial cells to the structure from which it arose -a hair follicle or eccrine sweat gland. 6,7 Secondary milia develop following certain triggers, including trauma -speci cally dermabrasion, 16 after subepidermal bullous disorders such as bullous pemphigoid, 17,18 following topical steroid therapy (where other features of steroid use including atrophy and telangiectasia may be seen), 18 following use of topical 5-uorouracil cream, following the use of acitretin in the treatment of 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 148 A Lee and WAD Grif ths Multiple milia due to radiotherapy Multiple primary milia are seen in association with various familial syndromes including the Brooke-Spiegler syndrome, Rombo syndrome and Bazex-Dupré-Christol syndrome.…”

Multiple Eruptive Milia in a 15‐year‐old Boy

“…Secondary milia arise as a cutaneous reaction to traumatic stimuli or pathologically altered integument and are distributed at the involved body sites ( 3). They may form during the course of vesicular or bullous eruptions, including porphyria cutanea tarda, bullous lichen planus, dystrophic epidermolysis bullosa, herpes zoster ( 3), lichen sclerosis et atrophicus, and bullous pemphigoid ( 4), second degree burns ( 3), autologous skin transplantation ( 2), dermabrasion ( 5), radiation ( 6), topical application of steroids ( 7) and 5‐FU ( 8), and after the clearing of inflammatory skin conditions including acne vulgaris ( 1), erysipelas ( 9), and allergic contact dermatitis ( 10). Possible cases of secondary milia arising from the use of benoxaprofen and acitretin administration have been documented ( 11, 12).…”

Lichen planus associated with milia

“…These conditions are characterized by involvement of the basement membrane zone with disruption of adjacent adnexal structures. Secondary milia are also seen following dermabrasion, 4 and have been reported less frequently in inflammatory dermatoses such as acute dermatitis and discoid lupus erythematosus 5,6 and during the treatment of mycosis fungoides. 7 Milia do not appear to be a recognized feature of lichen planus (LP).…”