Formation of bioactive highly porous polymer matrixes for tissue engineering

Bogorodskii, S. E.; Василец, В. Н.; Кротова, Л. И.; Минаева, С. А.; Миронов, А. Н.; Немец, Е. А.; Surguchenko, V. A.; Попов, В. К.; Sevast'yanov, V. I.

doi:10.1134/s2075113313050043

Cited by 9 publications

(1 citation statement)

References 17 publications

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“…Specific features of foaming and evolution of the foamed media structure arouse interest because, on the one hand, foam-like materials are widely applied in the technological sphere-from biomedical to airspace technology. In particular, tissue engineering broadly applies processes of foaming biosoluble polymers with the use of above-critical and subcritical plasticizing agents in order to create highly-porous matrices for cell cultures growth [1,2]. On the other hand, foamed media are evolving structures that demonstrate various fundamental features in their evolution caused by primary processes in their structural elements (bubbles, bubble boundaries, areas of crossing boundaries (Plato-Gibbs channels), and nodes of Plato-Gibbs channels network at a local level.…”

Section: Introductionmentioning

confidence: 99%

Evolution of Foamed Liquids Structure

Tumachev

Gavrilov

Лихтер

et al. 2018

J. Synch. Investig.

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In this article the conducted experiments resulted in identifying a power nature of dependence of an average radius of bubbles in the model foam metastable samples on time with a value close to 0.5. The special experimental setup has been developed for studying the dependence of the average radius of gas bubbles in the model foam metastable samples on time. Within the assumption of a thermally-activated mechanism of the gas phase diffusion through bubble walls, the analysis of temperature influence on behavior of average radius dependences on time allowed to estimate molar energy of the process activation.

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Section: Introductionmentioning

confidence: 99%

Evolution of Foamed Liquids Structure

Tumachev

Gavrilov

Лихтер

et al. 2018

J. Synch. Investig.

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Bioresorbable polymer matrices impregnated with BMP-2

Минаева

Антонов

Vasilyev

et al. 2019

IOP Conf. Ser.: Earth Environ. Sci.

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Bioresorbable matrices from poly(lactic-co-glycolic acid) containing therapeutically significant concentrations of bone morphogenetic protein 2 (BMP-2) was formed by super-critical fluid encapsulation and surface-selective laser sintering. Biocompatibility of these matrices and the kinetics of BMP-2 release from their volume into physiological saline was investigated. It was shown experimentally that the release of BMP-2 was almost uniform for 15 days. The subsequent use of laser sintering contributed to a longer retention of BMP-2. High cytocompatibility of the obtained matrices with cultures of mesenchymal stem cells was shown in vitro.

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