B. Kamm, M. Kamm, K. Richter, W. Reimann, A. Siebert
A fermentation process for manufacturing 1,4-piperazinium-(~~)-dilactate from renewable raw materials and a method for processing this product into LL-dilactide are described. Lactic acid fermentation with Lactobacillus paracasei was modified in such a way that pH control occurred by using an aqueous solution of piperazine as a correcting agent instead of sodium hydroxide solution. The production of a stoichiometrically composed piperazinium lactate was possible when the pH was 5.0. From 5.0 kg of glucose and…
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