Forensic effectiveness and genetic distribution of 23 autosomal STRs included in Verifiler PlusTM multiplex in a population sample from Madhya Pradesh, India

Shrivastava, Pankaj; Kaitholia, Kamlesh; Kumawat, R. K.; Dixit, Shivani; Dash, Hirak Ranjan; Srivastava, Ankit; Baroniya, Yash; Mishra, Aditi; Kushwaha, Pushpesh; Rana, Manisha; Dixit, Akansha; Sarawagi, Tanya; Bhatt, Alay; Sharma, Harsh; Sinha, Moumita; Chaubey, Gyaneshwer

doi:10.1007/s00414-019-02172-4

Cited by 6 publications

(3 citation statements)

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“…Consistent with previous studies, TPOX was the least discriminative locus. While in this study FGA was the most informative locus, other studies have supported PentaE as the most powerful locus ( Rodriguez et al, 2015 ; Sheng et al, 2018 ; Castillo et al, 2019 ; Chen et al, 2019 ; Naji et al, 2019 ; Shrivastava et al, 2019 ; Vu et al, 2021 ). Overall, the 23 STR loci in Verifiler TM plus PCR amplification kit could be valuable for forensic investigation in Thailand and Laos.…”

Section: Resultscontrasting

confidence: 55%

Genetic Structure and Forensic Utility of 23 Autosomal STRs of the Ethnic Lao Groups From Laos and Thailand

et al. 2022

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The Lao Isan and Laotian are the major groups in the area of present-day northeastern Thailand and Laos, respectively. Several previous genetic and forensic studies indicated an admixed genetic structure of Lao Isan with the local Austroasiatic speaking groups, e.g. Khmer, whereas there is a paucity of reporting Laotian’s forensic short tandem repeats (STRs). Here, we newly generated 451 genotypes of seven Lao Isan and three Laotian populations (two Lao Lum and one Lao Thoeng) using 23 autosomal STRs embedded in VerifilerTM plus PCR Amplification kit. We reported allelic frequency and forensic parameters in different dataset: combined ethnic Lao groups, combined Lao Isan populations and combined Laotians. Overall, the forensic parameter results indicate that this set of STRs is suitable for forensic investigation. The anthropological results revealed the genetic homogeneity of Tai-Kadai speaking Lao groups from Thailand and Laos, consistent with previous studies, while the Austroasiatic speaking groups from southern Laos showed genetic relatedness to both Lao Isan and Khmer. In sum, STRs allelic frequency results can provide the genetic backgrounds of populations which is useful for anthropological research and also strengthens the regional forensic database in both countries.

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Section: Resultscontrasting

confidence: 55%

Genetic Structure and Forensic Utility of 23 Autosomal STRs of the Ethnic Lao Groups From Laos and Thailand

et al. 2022

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“…In India, recently several population studies based on STR markers have been published (Srivastava et al 2019a;Srivastava etal. 2019b;Shrivastava et al 2020).…”

Section: Development Of the Dna Technologymentioning

confidence: 99%

Impact of DNA evidence in criminal justice system: Indian legislative perspectives

Srivastava

Harshey

Das

et al. 2022

Egypt J Forensic Sci

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Background The scientific and technological advances along with the changing socio-economical standards of society have posed new challenges to the criminal justice system. With the changes in society and technology, there is also an increase in crime rate. Forensics provides the scientific proofs beyond the shadow of reasonable doubt and thus significantly contributes in criminal as well as civil investigations and legal matters. Main body of the abstract Discovery of DNA has opened new avenues and the advancement of DNA technology and its introduction into the court of law has provided extensive aid in the resolution of civil and criminal disputes. In India, the DNA technology was first introduced in a paternity dispute in 1989. However, the need for legislation and guidelines to support grounds for the use of DNA profiling for forensic purposes in India has been recognized for some time now. In July 2019, the DNA Technology (Use and Application) Bill 2019 was introduced in the Indian parliament. Short conclusion Herein, this article is focused on the current aspects of DNA based evidence in the Indian Criminal Justice system along with the associated issues, highlighting the need for specific DNA based legislation.

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“…A neighbour joining (NJ) tree (Fig. 2 a) based on the Nei's genetic distance, constructed using POPTREE-2 software, was used to investigate the genetic affinity between the studied (admixed and Teli ) populations and the reported Indian populations namely, the Konkanastha Brahmins (Maharashtra) [ 22 ]; the Mahadev Kolis (Maharashtra) [ 22 ]; the Iyengars (Tamil Nadu) [ 22 ]; the Kurumans (Tamil Nadu) [ 22 ]; the Yerukulas (Andhra Pradesh) [ 23 ]; the Koras (West Bengal) [ 24 ]; the Baniyas (Punjab) [ 25 ]; the population of Jharkhand [ 26 ]; the population of Uttar Pradesh [ 27 ]; the population of Rajasthan [ 28 ]; the populations of Central India [ 29 ]; and the pooled populations belonging to the geographical boundaries of India [ 30 ]. The NJ tree revealed that the studied admixed and Teli populations of Maharashtra pooled into one cluster with the Konkanastha Brahmin s of Maharashtra and the Kurumans of Tamil Nadu.…”

Section: Main Textmentioning

confidence: 99%

A study of genomic diversity in populations of Maharashtra, India, inferred from 20 autosomal STR markers

et al. 2021

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Objective This study was planned to evaluate the genetic diversity in the admixed and Teli (a Hindu caste) populations of Maharashtra, India using 20 autosomal Short Tandem Repeat (STR) genetic markers. We further investigated the genetic relatedness of the studied populations with other Indian populations. Results The studied populations showed a wide range of observed heterozygosity viz. 0.690 to 0.918 for the admixed population and 0.696 to 0.942 for the Teli population. This might be due to the multi-directional gene flow. The admixed and Teli populations also showed a high degree polymorphism which ranged from 0.652 to 0.903 and 0.644 to 0.902, respectively. Their combined value of matching probability for all the studied loci was 4.29 × 10–25 and 5.01 × 10–24, respectively. The results of Neighbor-Joining tree and Principal Component Analysis showed that the studied populations clustered with the general populations of Jharkhand, UttarPradesh, Rajasthan and Central Indian States, as well as with the specific populations of Maharashtra (Konkanastha Brahmins) and Tamil Nadu (Kurmans). Overall, the obtained data showed a high degree of forensic efficacy and would be useful for forensic applications as well as genealogical studies.

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Forensic effectiveness and genetic distribution of 23 autosomal STRs included in Verifiler PlusTM multiplex in a population sample from Madhya Pradesh, India

Cited by 6 publications

References 1 publication

Genetic Structure and Forensic Utility of 23 Autosomal STRs of the Ethnic Lao Groups From Laos and Thailand

Genetic Structure and Forensic Utility of 23 Autosomal STRs of the Ethnic Lao Groups From Laos and Thailand

Impact of DNA evidence in criminal justice system: Indian legislative perspectives

A study of genomic diversity in populations of Maharashtra, India, inferred from 20 autosomal STR markers

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