Follow-up Study of Drug Use, Depression, and Anxiety Reduction and Quality of Life in Addicts on Methadone Maintenance Therapy

Abstract

Background:This study aimed to evaluate reduced drug consumption, risky behaviors, depression, and anxiety and improved quality of life in addicts on methadone maintenance therapy (MMT) at baseline and six months after therapy. Methods: In this descriptive cross-sectional study, 275 addicts were selected by a random sampling method in 2017. The data collection tools consisted of four questionnaires including a demographic information questionnaire, the Beck depression inventory questionnaire, WHOQOL-26, and Spielberger Anxiety Inventory. Data analysis was done by SPSS20 software at a confidence level of 95%. Results: Based on the obtained results, after six months, MMT efficiency was 50.5% and no cases of intravenous injection were reported. The consumption of other drugs was significantly reduced (P < 0.05). The highest prevalence of depression was observed in cannabis and opium users. Depression decreased from 85.81% to 63.27%. The mean scores of quality of life and anxiety after MMT increased to 89.6 and 20.41, respectively. The most improvement was in the physical health domain (mean score of 64.11). Conclusions:The results showed improvements in all the four domains of physical health, psychological health, social relationship, and environment and reductions in depression and anxiety.

Comparison of psychiatric disorders in addicted patients treated with buprenorphine, methadone, and opium tincture in Iran

“…Our study showed anxiety in the methadone group is 27% (OR = 0.73; 95% CI 0.61-0.88) lower than the buprenorphine. This finding was consistent with some studies conducted in this field [22][23][24]. For example, the study of Dehkordi et al, with the aim of investigating the effect of methadone on depression, anxiety, and quality of life of addicts in Iran, indicates a reduction in situational anxiety after methadone administration [24].…”

“…For example, the study of Dehkordi et al, with the aim of investigating the effect of methadone on depression, anxiety, and quality of life of addicts in Iran, indicates a reduction in situational anxiety after methadone administration [24]. The study by Almasi et al Also showed that the mean score of anxiety decreased significantly after methadone administration (39.40 vs. 20.41) [23]. However, compared to some other studies, this alignment was not observed.…”

Relationship of Spiritual Well-being, Social Health, and Parent-Child Interaction with Health-Related Quality of Life in Parents of Children with Specific Learning Disorders

“…The health-related quality of life (HRQOL) can be used to predict the effects of diseases, damages, and infirmities, as well as to assess mental health (8). An individual's HRQOL is determined by various factors, including their physical health, mental health, level of independence, social relationships, personal beliefs, and relationship with their environment (9,10). Parent-child interaction is another factor that affects the HRQOL of parents of children with specific learning disabilities.…”