Follicular fluid protein content (FSH, LH, PG4, E2 and AMH) and polar body aneuploidy

Abstract

High FF FSH levels were associated with oocyte aneuploidy in women having undergone controlled ovarian hyperstimulation.

Relationship between follicular volume and oocyte competence, blastocyst development and live‐birth rate: optimal follicle size for oocyte retrieval

“…In our study, P in FF was significantly elevated in large follicles, but no significant correlation between P and oocyte maturity and competence was detected. Previously, higher intrafollicular P concentrations were reported to be associated with higher implantation rate, while other studies could not confirm these results. Furthermore, in our study, G–CSF, a cytokine postulated as a predictor of embryo quality and higher implantation rate, was not correlated with follicle size or oocyte competence.…”

Relationship between follicular volume and oocyte competence, blastocyst development and live‐birth rate: optimal follicle size for oocyte retrieval

“…In our study, P in FF was significantly elevated in large follicles, but no significant correlation between P and oocyte maturity and competence was detected. Previously, higher intrafollicular P concentrations were reported to be associated with higher implantation rate, while other studies could not confirm these results. Furthermore, in our study, G–CSF, a cytokine postulated as a predictor of embryo quality and higher implantation rate, was not correlated with follicle size or oocyte competence.…”

Can polymorphisms of AMH/AMHR2 affect ovarian stimulation outcomes? A systematic review and meta-analysis

“…In the analysis of MII oocytes, we found that even though the T allele carriers of AMH rs10407022 had significantly fewer oocytes and they tended to have more MII oocytes. Some studies have found that high follicular FSH levels could interfere with the meiotic division and increase aneuploidy rates of oocytes during IVF treatment [29,30]. Consistent with these findings, we found that the T allele carriers of AMH rs10407022 polymorphism tended to have lower basal FSH (data not shown).…”

The effect of follicular fluid-related hormones and vascular endothelial factor levels on the formation of high-quality embryos

“…Previous studies have shown that high concentrations of FSH and LH in the FF can promote oocyte maturation and fertilization, and that they are beneficial to the formation and development of embryos [6]. However, recent studies have shown that increase in FSH in the FF can lead to increase in the number of polar bodies and embryo aneuploidy [13,14]. Our results also showed that the number of high-quality embryos decreased in the group with a higher FSH level in the FF, thereby indicating that the concentration of FSH in the FF affects the quality of oocytes and embryos.…”

Relationship between follicular volume and oocyte competence, blastocyst development and live‐birth rate: optimal follicle size for oocyte retrieval

“…In our study, P in FF was significantly elevated in large follicles, but no significant correlation between P and oocyte maturity and competence was detected. Previously, higher intrafollicular P concentrations were reported to be associated with higher implantation rate, while other studies could not confirm these results. Furthermore, in our study, G–CSF, a cytokine postulated as a predictor of embryo quality and higher implantation rate, was not correlated with follicle size or oocyte competence.…”

Can polymorphisms of AMH/AMHR2 affect ovarian stimulation outcomes? A systematic review and meta-analysis

“…In the analysis of MII oocytes, we found that even though the T allele carriers of AMH rs10407022 had significantly fewer oocytes and they tended to have more MII oocytes. Some studies have found that high follicular FSH levels could interfere with the meiotic division and increase aneuploidy rates of oocytes during IVF treatment [29,30]. Consistent with these findings, we found that the T allele carriers of AMH rs10407022 polymorphism tended to have lower basal FSH (data not shown).…”

The effect of follicular fluid-related hormones and vascular endothelial factor levels on the formation of high-quality embryos

“…Previous studies have shown that high concentrations of FSH and LH in the FF can promote oocyte maturation and fertilization, and that they are beneficial to the formation and development of embryos [6]. However, recent studies have shown that increase in FSH in the FF can lead to increase in the number of polar bodies and embryo aneuploidy [13,14]. Our results also showed that the number of high-quality embryos decreased in the group with a higher FSH level in the FF, thereby indicating that the concentration of FSH in the FF affects the quality of oocytes and embryos.…”

Relationship between follicular volume and oocyte competence, blastocyst development and live‐birth rate: optimal follicle size for oocyte retrieval

“…In our study, P in FF was significantly elevated in large follicles, but no significant correlation between P and oocyte maturity and competence was detected. Previously, higher intrafollicular P concentrations were reported to be associated with higher implantation rate, while other studies could not confirm these results. Furthermore, in our study, G–CSF, a cytokine postulated as a predictor of embryo quality and higher implantation rate, was not correlated with follicle size or oocyte competence.…”

Can polymorphisms of AMH/AMHR2 affect ovarian stimulation outcomes? A systematic review and meta-analysis

“…In the analysis of MII oocytes, we found that even though the T allele carriers of AMH rs10407022 had significantly fewer oocytes and they tended to have more MII oocytes. Some studies have found that high follicular FSH levels could interfere with the meiotic division and increase aneuploidy rates of oocytes during IVF treatment [29,30]. Consistent with these findings, we found that the T allele carriers of AMH rs10407022 polymorphism tended to have lower basal FSH (data not shown).…”

The effect of follicular fluid-related hormones and vascular endothelial factor levels on the formation of high-quality embryos

“…Previous studies have shown that high concentrations of FSH and LH in the FF can promote oocyte maturation and fertilization, and that they are beneficial to the formation and development of embryos [6]. However, recent studies have shown that increase in FSH in the FF can lead to increase in the number of polar bodies and embryo aneuploidy [13,14]. Our results also showed that the number of high-quality embryos decreased in the group with a higher FSH level in the FF, thereby indicating that the concentration of FSH in the FF affects the quality of oocytes and embryos.…”