Focal Segmental Glomerulosclerosis Presenting as Acute Systolic Heart Failure

Mosseri, Maurice; Al-Bayati, Asseel; Udongwo, Ndausung; Alsaadi, Ennis; Patel, Swapnil; Sen, Shuvendu; Asif, Arif

doi:10.26502/acmcr.96550378

Cited by 1 publication

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“…An increased risk of acquiring FSGS among AAs has been seen with polymorphic variants (G1 and G2) in the Apolipoprotein 1 (APOL-1) gene [4,5]. Proteinuria, high creatinine, elevated blood pressure, and NS are some of the hallmarks of this disease [5]. Although our patient had both clinical and laboratory findings consistent with NS, an IR-guided renal biopsy was performed to confirm FSGS.…”

Section: Discussionmentioning

confidence: 83%

“…FSGS is commonly seen among AAs with a higher rate seen in men with a mean age ranging between 23 and 57 years old [3]. An increased risk of acquiring FSGS among AAs has been seen with polymorphic variants (G1 and G2) in the Apolipoprotein 1 (APOL-1) gene [4,5]. Proteinuria, high creatinine, elevated blood pressure, and NS are some of the hallmarks of this disease [5].…”

Section: Discussionmentioning

confidence: 99%

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A Life-Changing Diagnosis of Focal Segmental Glomerulosclerosis in a Young Hispanic Male

Kaliounji¹,

Farraj²,

Juta³

et al. 2021

Cureus

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Focal segmental glomerulosclerosis is a nephrotic syndrome characterized by significant proteinuria on urinalysis and sclerosis in parts of at least one glomerulus on biopsy. While primary cases are on the rise over the past two decades, it is important to rule out etiologies that cause secondary focal segmental glomerulosclerosis such as HIV and Hepatitis B. The prevalence of this disease over the past few decades has been notably higher in men and in particular African Americans. Here, we discuss a case of a 25-year-old Hispanic man who was found to have focal segmental glomerulosclerosis after initially presenting with facial and upper and lower extremity swelling.

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Section: Discussionmentioning

confidence: 83%