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Cited by 18 publications
(4 citation statements)
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References 12 publications
(4 reference statements)
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“…Moreover, they are similarly effective in attenuating both glomerulosclerosis and tubulointerstitial fibrosis [14][15][16][17][18]. However, Crenshaw et al [19] reviewed demographic, biopsy and treatment data in the charts of all patients entering the ESRD programme with a primary diagnosis of FSGS. They found that neither the ACEIs nor the CSs had significant impact on the progression to ESRD.…”
Section: Discussionmentioning
confidence: 99%
“…Moreover, they are similarly effective in attenuating both glomerulosclerosis and tubulointerstitial fibrosis [14][15][16][17][18]. However, Crenshaw et al [19] reviewed demographic, biopsy and treatment data in the charts of all patients entering the ESRD programme with a primary diagnosis of FSGS. They found that neither the ACEIs nor the CSs had significant impact on the progression to ESRD.…”
Section: Discussionmentioning
confidence: 99%
“…A few small studies of ACE inhibitors in patients with primary focal segmental glomerulosclerosis have shown reduction in proteinuria without slowing the progression of renal decline. [13][14][15][16][17] One retrospective study of 48 patients with biopsy-proven FSGS showed no additional antiproteinuric effect of adding steroids to an ACE inhibitor alone. 15 ACE inhibition in FSGS secondary to obesity, reflux nephropathy, reduced nephron mass, and sickle cell disease have shown 50% reductions in proteinuria with stabilization of renal function.…”
Section: Figure 1 Light Microscopy Of Renal Biopsy Revealing a Dark mentioning
confidence: 99%
“…18 Both ACE inhibition and significant weight loss (approximately a 10% reduction in body mass index), can significantly reduce proteinuria in obesity-related FSGS. 18,19 One retrospective study of 40 African-American patients with FSGS did not demonstrate any renoprotective benefit with either ACE inhibitors or steroids, 14 and African Americans with primary FSGS are generally believed to be less responsive to therapy. 20,21 Counseling sessions with this patient led to a strategy of maximizing ACE inhibition to achieve a goal BP <130/80 mm Hg, and reducing weight.…”
Section: Figure 1 Light Microscopy Of Renal Biopsy Revealing a Dark mentioning
confidence: 99%
“…African-Americans who are not infected with HIV also have a high frequency and poor prognosis of other similar renal diseases, such as focal segmental glomerulosclerosis. 14 These findings suggest a general predisposition to renal disease among African-Americans. 12,15 In children with HIV, the rate of HIVAN has been reported as 10-15%.…”
mentioning
confidence: 90%