Focal epileptic spasms, involving one leg, manifesting during the clinical course of west syndrome (WS)

Tanoue, Koji; Oguni, Hirokazu; Nakayama, Naoko; Sasaki, Kaori; Ito, Yasushi; Imai, Kaoru S.; Ōsawa, Makiko

doi:10.1016/j.braindev.2007.06.005

Cited by 8 publications

(9 citation statements)

References 7 publications

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“…Clinical and EEG pictures of epilepsy associated with cortical malformation have been shown to be diverse, manifesting not only with IS and focal epilepsy but also with IS with focal features that later evolved into focal epilepsy [16,21]. A few case reports showed the presence of focal spasms in patients with fIS, indicating that focal cortical lesions can produce asymmetric ES [22,23]. There have also been several reports indicating that surgical success largely depended on the localized MRI lesion that was responsible for generation of the seizures [11,13,14].…”

Section: Discussionmentioning

confidence: 98%

“…Finally, 11 patients developed focal seizures at onset ages ranging from 11 to 96 months, with a median of 31 months ( Fig. 1: Cases 4,7,9,[11][12][13][14][15][16]19,23). Seven patients had complex partial seizures with impairment in consciousness only, three patients showed tonic posturing, and one patient demonstrated unilateral clonic seizures.…”

Section: Clinical Course Eeg Evolutional Changes and Seizure Relapsementioning

confidence: 94%

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A long-term, clinical study on symptomatic infantile spasms with focal features

Fujii

Oguni

Hirano

et al. 2013

Brain and Development

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Section: Discussionmentioning

confidence: 98%

Section: Clinical Course Eeg Evolutional Changes and Seizure Relapsementioning

confidence: 94%

A long-term, clinical study on symptomatic infantile spasms with focal features

Fujii

Oguni

Hirano

et al. 2013

Brain and Development

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“…A waveform which has been found to emerge in patients with brain inflammations is the slow biphasic complex (SBC) [7-9, 13, 15, 23, 26, 32, 50]. After being observed during decades in EEG traces of patients with different pathologies (e.g., human immunodeficiency virus-HIV [7,8], West syndrome [15,50], encephalitis [7] and Rasmussen's syndrome [9]), we proposed an automated method to identify it [37]. We found a high correlation of the number and amplitude of the identified SBCs with the severity of encephalitis.…”

Section: Introductionmentioning

confidence: 99%

Automated diagnosis of encephalitis in pediatric patients using EEG rhythms and slow biphasic complexes

2020

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Slow biphasic complexes (SBC) have been identified in the EEG of patients suffering for inflammatory brain diseases. Their amplitude, location and frequency of appearance were found to correlate with the severity of encephalitis. Other characteristics of SBCs and of EEG traces of patients could reflect the grade of pathology. Here, EEG rhythms are investigated together with SBCs for a better characterization of encephalitis. EEGs have been acquired from pediatric patients: ten controls and ten encephalitic patients. They were split by neurologists into five classes of different severity of the pathology. The relative power of EEG rhythms was found to change significantly in EEGs labeled with different severity scores. Moreover, a significant variation was found in the last seconds before the appearance of an SBC. This information and quantitative indexes characterizing the SBCs were used to build a binary classification decision tree able to identify the classes of severity. True classification rate of the best model was 76.1% (73.5% with leave-one-out test). Moreover, the classification errors were among classes with similar severity scores (precision higher than 80% was achieved considering three instead of five classes). Our classification method may be a promising supporting tool for clinicians to diagnose, assess and make the follow-up of patients with encephalitis.

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“…SBCs have been observed in patients with brain inflammations [13,15,28,29] . We have developed an automated processing method to identify SBCs and we have shown in previous studies a good correlation between their onset and the severity of encephalitis [14,18] .…”

Section: Discussionmentioning

confidence: 99%

The relation between lesions and localization of sources of slow biphasic complexes in encephalitis

Valério¹,

Rivera²,

Mesin³

2020

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Slow biphasic complexes (SBC) were found in the electroencephalogram (EEG) of patients with inflammations of the brain. We have developed an automated method to identify them and proved that they represent a sensitive marker of the severity of encephalitis. Here we focus on another property of SBCs, i.e., the localization of their sources. We present two encephalitic patients, showing lesions in the magnetic resonance images, which are either spread in the brain or focused on the left hemisphere, respectively. Applying a source localization algorithm to the identified SBCs, we found either a diffused or a left-focused distribution, respectively. This result further suggests a relation between neuroinflammation and appearance of SBCs, indicating that their distribution reflects in part the localization of brain lesions. This promising result extends the information that can be extracted from EEG, promoting the reduction of expensive or invasive measurements in encephalitic patients.

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Focal epileptic spasms, involving one leg, manifesting during the clinical course of west syndrome (WS)

Cited by 8 publications

References 7 publications

A long-term, clinical study on symptomatic infantile spasms with focal features

A long-term, clinical study on symptomatic infantile spasms with focal features

Automated diagnosis of encephalitis in pediatric patients using EEG rhythms and slow biphasic complexes

The relation between lesions and localization of sources of slow biphasic complexes in encephalitis

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