Fluticasone versus HFA-beclomethasone dipropionate for chronic asthma in adults and children

Small-particle Inhaled Corticosteroid as First-line or Step-up Controller Therapy in Childhood Asthma

“…3 The Cochrane analysis that compared small-particle hydrofluoroalkane-beclomethasone and fluticasone for children with asthma was limited because only 2 studies were found. 2 Robroeks et al 20 reported no difference between 12-week therapy with small-particle beclomethasone or fluticasone in either anti-inflammatory effects or clinical outcomes for 33 children with asthma in a small crossover study, although children at study start had normal lung function and generally well-controlled asthma. van Aalderen et al 12,21 showed that small-particle beclomethasone and fluticasone had similar effects on lung function and overall asthma control in an 18-week ICS step-down study in 280 children aged 5 to 12 years with mild-to-moderate asthma.…”

Small-particle Inhaled Corticosteroid as First-line or Step-up Controller Therapy in Childhood Asthma

“…3 The Cochrane analysis that compared small-particle hydrofluoroalkane-beclomethasone and fluticasone for children with asthma was limited because only 2 studies were found. 2 Robroeks et al 20 reported no difference between 12-week therapy with small-particle beclomethasone or fluticasone in either anti-inflammatory effects or clinical outcomes for 33 children with asthma in a small crossover study, although children at study start had normal lung function and generally well-controlled asthma. van Aalderen et al 12,21 showed that small-particle beclomethasone and fluticasone had similar effects on lung function and overall asthma control in an 18-week ICS step-down study in 280 children aged 5 to 12 years with mild-to-moderate asthma.…”

Intranasal corticosteroid users in The Netherlands: A drug utilization study

“…Individually, these treatments have been studied extensively and are considered safe, with the risk of side effects being considered low. 28 , 29 , 30 , 31 , 32 , 33 , 34 However, when these corticosteroid-containing drugs are combined, the risk of more serious, corticosteroid-related side effects (eg, growth retardation, osteoporosis, adrenal cortical hypofunction, and Cushing syndrome) may increase. 18 , 19 , 35 , 36 , 37 , 38 Patients, particularly children, are vulnerable for the development of these side effects.…”

Cost-effectiveness of initiating extrafine- or standard size-particle inhaled corticosteroid for asthma in two health-care systems: a retrospective matched cohort study

“… 33 Prior studies comparing extrafine beclomethasone and fluticasone were short-term (3–12 weeks) randomised trials that did not evaluate cost-effectiveness. 34 …”

Small-particle Inhaled Corticosteroid as First-line or Step-up Controller Therapy in Childhood Asthma

“…3 The Cochrane analysis that compared small-particle hydrofluoroalkane-beclomethasone and fluticasone for children with asthma was limited because only 2 studies were found. 2 Robroeks et al 20 reported no difference between 12-week therapy with small-particle beclomethasone or fluticasone in either anti-inflammatory effects or clinical outcomes for 33 children with asthma in a small crossover study, although children at study start had normal lung function and generally well-controlled asthma. van Aalderen et al 12,21 showed that small-particle beclomethasone and fluticasone had similar effects on lung function and overall asthma control in an 18-week ICS step-down study in 280 children aged 5 to 12 years with mild-to-moderate asthma.…”

Intranasal corticosteroid users in The Netherlands: A drug utilization study

“…Individually, these treatments have been studied extensively and are considered safe, with the risk of side effects being considered low. 28 , 29 , 30 , 31 , 32 , 33 , 34 However, when these corticosteroid-containing drugs are combined, the risk of more serious, corticosteroid-related side effects (eg, growth retardation, osteoporosis, adrenal cortical hypofunction, and Cushing syndrome) may increase. 18 , 19 , 35 , 36 , 37 , 38 Patients, particularly children, are vulnerable for the development of these side effects.…”

Cost-effectiveness of initiating extrafine- or standard size-particle inhaled corticosteroid for asthma in two health-care systems: a retrospective matched cohort study

“… 33 Prior studies comparing extrafine beclomethasone and fluticasone were short-term (3–12 weeks) randomised trials that did not evaluate cost-effectiveness. 34 …”

Small-particle Inhaled Corticosteroid as First-line or Step-up Controller Therapy in Childhood Asthma

“…3 The Cochrane analysis that compared small-particle hydrofluoroalkane-beclomethasone and fluticasone for children with asthma was limited because only 2 studies were found. 2 Robroeks et al 20 reported no difference between 12-week therapy with small-particle beclomethasone or fluticasone in either anti-inflammatory effects or clinical outcomes for 33 children with asthma in a small crossover study, although children at study start had normal lung function and generally well-controlled asthma. van Aalderen et al 12,21 showed that small-particle beclomethasone and fluticasone had similar effects on lung function and overall asthma control in an 18-week ICS step-down study in 280 children aged 5 to 12 years with mild-to-moderate asthma.…”

Intranasal corticosteroid users in The Netherlands: A drug utilization study

“…Individually, these treatments have been studied extensively and are considered safe, with the risk of side effects being considered low. 28 , 29 , 30 , 31 , 32 , 33 , 34 However, when these corticosteroid-containing drugs are combined, the risk of more serious, corticosteroid-related side effects (eg, growth retardation, osteoporosis, adrenal cortical hypofunction, and Cushing syndrome) may increase. 18 , 19 , 35 , 36 , 37 , 38 Patients, particularly children, are vulnerable for the development of these side effects.…”

Cost-effectiveness of initiating extrafine- or standard size-particle inhaled corticosteroid for asthma in two health-care systems: a retrospective matched cohort study

“… 33 Prior studies comparing extrafine beclomethasone and fluticasone were short-term (3–12 weeks) randomised trials that did not evaluate cost-effectiveness. 34 …”