Fluphenazine versus low-potency first generation antipsychotic drugs for schizophrenia

Salivary hypofunction: An update on aetiology, diagnosis and therapeutics

“…35 Furthermore, because these medications act on the central nervous system, they can cause alterations in saliva by means of indirect actions on the salivary glands. Antipsychotics [36][37][38] , antihistamines, 39 drugs for overactive bladder, 40,41 and anticholinergic bronchodilators 42 also show anticholinergic activity, causing salivary hypofunction.…”

Salivary hypofunction: An update on aetiology, diagnosis and therapeutics

“…35 Furthermore, because these medications act on the central nervous system, they can cause alterations in saliva by means of indirect actions on the salivary glands. Antipsychotics [36][37][38] , antihistamines, 39 drugs for overactive bladder, 40,41 and anticholinergic bronchodilators 42 also show anticholinergic activity, causing salivary hypofunction.…”

Osteocyte-Driven Downregulation of Snail Restrains Effects of Drd2 Inhibitors on Mammary Tumor Cells

“…In this study, we focused on two FDA-approved drugs, Fluphenazine (FP) and Trifluoperazine (TFP), and evaluated their roles in tumor-bone interactions. These two agents are modulators of dopaminergic signaling and currently used as antipsychotic medications (10,11). The dopamine system is involved in many neurological functions (12), but it is also important in other tissues, such as the cardiovascular and skeletal systems (13,14).…”

Salivary hypofunction: An update on aetiology, diagnosis and therapeutics

“…35 Furthermore, because these medications act on the central nervous system, they can cause alterations in saliva by means of indirect actions on the salivary glands. Antipsychotics [36][37][38] , antihistamines, 39 drugs for overactive bladder, 40,41 and anticholinergic bronchodilators 42 also show anticholinergic activity, causing salivary hypofunction.…”

Osteocyte-Driven Downregulation of Snail Restrains Effects of Drd2 Inhibitors on Mammary Tumor Cells

“…In this study, we focused on two FDA-approved drugs, Fluphenazine (FP) and Trifluoperazine (TFP), and evaluated their roles in tumor-bone interactions. These two agents are modulators of dopaminergic signaling and currently used as antipsychotic medications (10,11). The dopamine system is involved in many neurological functions (12), but it is also important in other tissues, such as the cardiovascular and skeletal systems (13,14).…”

Salivary hypofunction: An update on aetiology, diagnosis and therapeutics

“…35 Furthermore, because these medications act on the central nervous system, they can cause alterations in saliva by means of indirect actions on the salivary glands. Antipsychotics [36][37][38] , antihistamines, 39 drugs for overactive bladder, 40,41 and anticholinergic bronchodilators 42 also show anticholinergic activity, causing salivary hypofunction.…”

Osteocyte-Driven Downregulation of Snail Restrains Effects of Drd2 Inhibitors on Mammary Tumor Cells

“…In this study, we focused on two FDA-approved drugs, Fluphenazine (FP) and Trifluoperazine (TFP), and evaluated their roles in tumor-bone interactions. These two agents are modulators of dopaminergic signaling and currently used as antipsychotic medications (10,11). The dopamine system is involved in many neurological functions (12), but it is also important in other tissues, such as the cardiovascular and skeletal systems (13,14).…”