Fluoxetine versus other types of pharmacotherapy for depression

Abstract

There are statistically significant differences in terms of efficacy and tolerability between fluoxetine and certain ADs, but the clinical meaning of these differences is uncertain, and no definitive implications for clinical practice can be drawn. From a clinical point of view the analysis of antidepressants' safety profile (adverse effect and suicide risk) remains of crucial importance and more reliable data about these outcomes are needed. Waiting for more robust evidence, treatment decisions should be based on considerations of clinical history, drug toxicity, patient acceptability, and cost. We need for large, pragmatic trials, enrolling heterogeneous populations of patients with depression to generate clinically relevant information on the benefits and harms of competitive pharmacological options. A meta-analysis of individual patient data from the randomised trials is clearly necessary.

Prescribing Practice of Antidepressant Drugs at Outpatient Department of a Tertiary Care Teaching Hospital in Bangladesh

“…SSRIs are effective in the treatment of MDD. It is demonstrated in many studies that the efficacy of SSRIs is superior to other antidepressant medications, mainly Tetracyclic Atidepressant (TCAs) (Anderson, 2000;Arroll et al, 2009;Cipriani et al, 2005). Result from the current study shows that new antidepressant drugs (SSRIs, SNRIs, NRIs, etc.)…”

Prescribing Practice of Antidepressant Drugs at Outpatient Department of a Tertiary Care Teaching Hospital in Bangladesh

“…SSRIs are effective in the treatment of MDD. It is demonstrated in many studies that the efficacy of SSRIs is superior to other antidepressant medications, mainly Tetracyclic Atidepressant (TCAs) (Anderson, 2000;Arroll et al, 2009;Cipriani et al, 2005). Result from the current study shows that new antidepressant drugs (SSRIs, SNRIs, NRIs, etc.)…”

Intervention options: Depression & Cardiovascular Disease during Covid-19 Pandemia

“…Sertraline had a positive effect in the reduction of depression without increasing the risk of negative cardio effects, while escitalopram led to the reduction of major adverse cardiac events within 6 months after the ACS [60]. Other studies testing the efficac of paroxetine and fluoxetine versus placebo and versus nortriptyline, which belongs to the drug-class of Tricyclic antidepressant (TCA) shared similar results [70]. Paroxetine and Fluoxetine led to the reduction of depressive symptoms, without having the negative effects on cardiac side like in the case of nortriptyline, where ventricular arrhythmias have been presented [47].…”

Characteristics of hospital encounters and associated economic burden of patients with major depressive disorder and acute suicidal ideation or behavior

“……”

Prescribing Practice of Antidepressant Drugs at Outpatient Department of a Tertiary Care Teaching Hospital in Bangladesh

“…SSRIs are effective in the treatment of MDD. It is demonstrated in many studies that the efficacy of SSRIs is superior to other antidepressant medications, mainly Tetracyclic Atidepressant (TCAs) (Anderson, 2000;Arroll et al, 2009;Cipriani et al, 2005). Result from the current study shows that new antidepressant drugs (SSRIs, SNRIs, NRIs, etc.)…”

Intervention options: Depression & Cardiovascular Disease during Covid-19 Pandemia

“…Sertraline had a positive effect in the reduction of depression without increasing the risk of negative cardio effects, while escitalopram led to the reduction of major adverse cardiac events within 6 months after the ACS [60]. Other studies testing the efficac of paroxetine and fluoxetine versus placebo and versus nortriptyline, which belongs to the drug-class of Tricyclic antidepressant (TCA) shared similar results [70]. Paroxetine and Fluoxetine led to the reduction of depressive symptoms, without having the negative effects on cardiac side like in the case of nortriptyline, where ventricular arrhythmias have been presented [47].…”

Characteristics of hospital encounters and associated economic burden of patients with major depressive disorder and acute suicidal ideation or behavior

“……”

Prescribing Practice of Antidepressant Drugs at Outpatient Department of a Tertiary Care Teaching Hospital in Bangladesh

“…SSRIs are effective in the treatment of MDD. It is demonstrated in many studies that the efficacy of SSRIs is superior to other antidepressant medications, mainly Tetracyclic Atidepressant (TCAs) (Anderson, 2000;Arroll et al, 2009;Cipriani et al, 2005). Result from the current study shows that new antidepressant drugs (SSRIs, SNRIs, NRIs, etc.)…”

Intervention options: Depression & Cardiovascular Disease during Covid-19 Pandemia

“…Sertraline had a positive effect in the reduction of depression without increasing the risk of negative cardio effects, while escitalopram led to the reduction of major adverse cardiac events within 6 months after the ACS [60]. Other studies testing the efficac of paroxetine and fluoxetine versus placebo and versus nortriptyline, which belongs to the drug-class of Tricyclic antidepressant (TCA) shared similar results [70]. Paroxetine and Fluoxetine led to the reduction of depressive symptoms, without having the negative effects on cardiac side like in the case of nortriptyline, where ventricular arrhythmias have been presented [47].…”

Characteristics of hospital encounters and associated economic burden of patients with major depressive disorder and acute suicidal ideation or behavior

“……”