Fluoroquinolones for treating typhoid and paratyphoid fever (enteric fever)

Abstract

Trials were small and methodological quality varied. In adults, fluoroquinolones may be better for reducing clinical relapse rates compared to chloramphenicol. Data are limited for other comparisons, particularly in children.

Antimicrobial Resistance among Salmonella and Shigella Isolates in Five Canadian Provinces (1997 to 2000)

“…Therefore, our results may be more representative for Shigella than for Salmonella. (8). Among the Salmonella isolates in our study, we observed higher rates of resistance to clinically important antimicrobials than previously reported.…”

Antimicrobial Resistance among Salmonella and Shigella Isolates in Five Canadian Provinces (1997 to 2000)

“…Therefore, our results may be more representative for Shigella than for Salmonella. (8). Among the Salmonella isolates in our study, we observed higher rates of resistance to clinically important antimicrobials than previously reported.…”

Assessment of clinical profile, antibiotic sensitivity and prescription pattern in blood culture positive enteric fever among pediatric and adult patients admitted in a tertiary care hospital: a prospective study

“…It has been shown that defervescence takes anywhere from 3 to 6 days after initiation of therapy. 16 The difference between mean defervescence time in those patients, who received ceftriaxone only and those who received more than one antibiotic in combination was not statistically significant. Similarly, in the study, there was no significant difference in time to defervescence in the above mentioned groups.…”

Fever in the vaccinated returning traveller

“…9 Therefore, once sensitivities are known ciprofloxacin is a good choice of antibiotic, but caution is advised because sensitivity only to nalidixic acid confirms true quinolone sensitivity. 10 It is worth noting that even if resistant to fluoroquinolones the bacteria may be sensitive to amoxicillin or chloramphenicol, which are recommended by WHO as "alternative" effective drugs for treating enteric fever.…”

Antimicrobial Resistance among Salmonella and Shigella Isolates in Five Canadian Provinces (1997 to 2000)

“…Therefore, our results may be more representative for Shigella than for Salmonella. (8). Among the Salmonella isolates in our study, we observed higher rates of resistance to clinically important antimicrobials than previously reported.…”

Assessment of clinical profile, antibiotic sensitivity and prescription pattern in blood culture positive enteric fever among pediatric and adult patients admitted in a tertiary care hospital: a prospective study

“…It has been shown that defervescence takes anywhere from 3 to 6 days after initiation of therapy. 16 The difference between mean defervescence time in those patients, who received ceftriaxone only and those who received more than one antibiotic in combination was not statistically significant. Similarly, in the study, there was no significant difference in time to defervescence in the above mentioned groups.…”

Fever in the vaccinated returning traveller

“…9 Therefore, once sensitivities are known ciprofloxacin is a good choice of antibiotic, but caution is advised because sensitivity only to nalidixic acid confirms true quinolone sensitivity. 10 It is worth noting that even if resistant to fluoroquinolones the bacteria may be sensitive to amoxicillin or chloramphenicol, which are recommended by WHO as "alternative" effective drugs for treating enteric fever.…”

Antimicrobial Resistance among Salmonella and Shigella Isolates in Five Canadian Provinces (1997 to 2000)

“…Therefore, our results may be more representative for Shigella than for Salmonella. (8). Among the Salmonella isolates in our study, we observed higher rates of resistance to clinically important antimicrobials than previously reported.…”

Assessment of clinical profile, antibiotic sensitivity and prescription pattern in blood culture positive enteric fever among pediatric and adult patients admitted in a tertiary care hospital: a prospective study

“…It has been shown that defervescence takes anywhere from 3 to 6 days after initiation of therapy. 16 The difference between mean defervescence time in those patients, who received ceftriaxone only and those who received more than one antibiotic in combination was not statistically significant. Similarly, in the study, there was no significant difference in time to defervescence in the above mentioned groups.…”

Fever in the vaccinated returning traveller

“…9 Therefore, once sensitivities are known ciprofloxacin is a good choice of antibiotic, but caution is advised because sensitivity only to nalidixic acid confirms true quinolone sensitivity. 10 It is worth noting that even if resistant to fluoroquinolones the bacteria may be sensitive to amoxicillin or chloramphenicol, which are recommended by WHO as "alternative" effective drugs for treating enteric fever.…”