Fluorophotometry and the Blood-Ocular Barrier in Experimental Systemic Hypertension

Fluorophotometric Evaluation of Blood-Retinal Barrier Permeability in Patients with Essential Hypertension

“…VF is useful in the detection of early BRB breakdown [2]. In the literature there are few publications dealing with the fluorophotometric examination of P BRB in patients with essential hypertension (EH) [3, 4, 5, 6, 7]. Smoking has a negative effect on the vascular endothelium [8].…”

“…Only a few studies dealt with the P BRB in hypertensive patients [3, 4, 5, 6, 7]but they did not use the protocol recommended by ECNOF [13], which makes any comparisons difficult. Dutton et al [4]showed in an experimental study of rats with severe EH the increase of fluorescein concentration in the anterior chamber and in the vitreous. The normalization of BP led to the decrease of P BRB to normal values.…”

Fluorophotometric Evaluation of Blood-Retinal Barrier Permeability in Patients with Essential Hypertension

“…VF is useful in the detection of early BRB breakdown [2]. In the literature there are few publications dealing with the fluorophotometric examination of P BRB in patients with essential hypertension (EH) [3, 4, 5, 6, 7]. Smoking has a negative effect on the vascular endothelium [8].…”

“…Only a few studies dealt with the P BRB in hypertensive patients [3, 4, 5, 6, 7]but they did not use the protocol recommended by ECNOF [13], which makes any comparisons difficult. Dutton et al [4]showed in an experimental study of rats with severe EH the increase of fluorescein concentration in the anterior chamber and in the vitreous. The normalization of BP led to the decrease of P BRB to normal values.…”

Fluorophotometric Evaluation of Blood-Retinal Barrier Permeability in Patients with Essential Hypertension

“…VF is useful in the detection of early BRB breakdown [2]. In the literature there are few publications dealing with the fluorophotometric examination of P BRB in patients with essential hypertension (EH) [3, 4, 5, 6, 7]. Smoking has a negative effect on the vascular endothelium [8].…”

“…Only a few studies dealt with the P BRB in hypertensive patients [3, 4, 5, 6, 7]but they did not use the protocol recommended by ECNOF [13], which makes any comparisons difficult. Dutton et al [4]showed in an experimental study of rats with severe EH the increase of fluorescein concentration in the anterior chamber and in the vitreous. The normalization of BP led to the decrease of P BRB to normal values.…”

Fluorophotometric Evaluation of Blood-Retinal Barrier Permeability in Patients with Essential Hypertension

“…VF is useful in the detection of early BRB breakdown [2]. In the literature there are few publications dealing with the fluorophotometric examination of P BRB in patients with essential hypertension (EH) [3, 4, 5, 6, 7]. Smoking has a negative effect on the vascular endothelium [8].…”

“…Only a few studies dealt with the P BRB in hypertensive patients [3, 4, 5, 6, 7]but they did not use the protocol recommended by ECNOF [13], which makes any comparisons difficult. Dutton et al [4]showed in an experimental study of rats with severe EH the increase of fluorescein concentration in the anterior chamber and in the vitreous. The normalization of BP led to the decrease of P BRB to normal values.…”