Fluorides for the prevention of white spots on teeth during fixed brace treatment

Prevention of demineralization during multi‐bracketed fixed orthodontic treatment: An overview of systematic reviews

“…One author of the conference abstract was contacted by email to obtain complete information about the systematic review, but no information could be obtained. Finally, 29 reviews (equal to 30 published papers 11‐40 ; since two of the papers 12,13 were almost identical, they were considered only once) met the eligibility criteria and were included in the present overview. The value of Cohen’s kappa for final inclusion after full‐text reading of the 86 articles among two reviewers (SD and MS) was found to be 0.85, indicating substantial agreement.…”

“…Three of the included reviews 12,14,15 were Cochrane reviews, of which two reviews 14,15 were the updates of the Cochrane review published in 2004 12 . Ten of the non‐Cochrane reviews had their protocols registered at PROSPERO, which were accessible for additional information 12,22,25,28,30,35,36,37,38,40 . Although Cochrane reviews are updated regularly, and the most updated review should be considered for making clinical decisions, the two older versions of the Cochrane reviews 12,14 were included as they are freely available online for the clinicians to make their clinical decisions.…”

“…Eighteen reviews 12,13,14,15,16,17,21,26,28,30,32,33,34,35,36,38,39,40 (including three Cochrane reviews) focused on the role of any form of fluorides (professionally applied, self‐applied, or fluoride‐releasing materials), and two other reviews 22,25 focused on the role of fluorides with calcium phosphopeptide‐amorphous calcium phosphate (CPP‐ACP). Three reviews 30,32,34 focused specifically on the role of fluoride varnishes, whereas one review focused on the role of professionally applied topical fluorides 35 .…”

“…Only 5 reviews 11,13,14,38,39 included in this overview were assessed by the authors to be of low risk of overall bias, whereas 23 reviews (equal to 24 published papers) 12,15,16,17,18,19,20,21,22,23,25,26,27,28,29,30,31,32,33,34,35,36,37,40 were assessed to be of high risk of overall bias, and one review 24 was of unclear risk of bias. The most common domain assessed to be of high risk or unclear risk was domain 1 (study eligibility criteria; 86.2%), followed by domains 2 and 3 (identification and selection of studies and data collection and study appraisal, respectively) with 51.7% of the reviews having high or unclear risk.…”

“…The summary of the 29 included reviews (30 published papers) is presented in Table 1. Three of the included reviews 12,14,15 were Cochrane reviews, of which two reviews 14,15 were the updates of the Cochrane review published in 2004 12 . Ten of the non‐Cochrane reviews had their protocols registered at PROSPERO, which were accessible for additional information 12,22,25,28,30,35,36,37,38,40 .…”

Prevention of demineralization during multi‐bracketed fixed orthodontic treatment: An overview of systematic reviews

“…One author of the conference abstract was contacted by email to obtain complete information about the systematic review, but no information could be obtained. Finally, 29 reviews (equal to 30 published papers 11‐40 ; since two of the papers 12,13 were almost identical, they were considered only once) met the eligibility criteria and were included in the present overview. The value of Cohen’s kappa for final inclusion after full‐text reading of the 86 articles among two reviewers (SD and MS) was found to be 0.85, indicating substantial agreement.…”

“…Three of the included reviews 12,14,15 were Cochrane reviews, of which two reviews 14,15 were the updates of the Cochrane review published in 2004 12 . Ten of the non‐Cochrane reviews had their protocols registered at PROSPERO, which were accessible for additional information 12,22,25,28,30,35,36,37,38,40 . Although Cochrane reviews are updated regularly, and the most updated review should be considered for making clinical decisions, the two older versions of the Cochrane reviews 12,14 were included as they are freely available online for the clinicians to make their clinical decisions.…”

“…Eighteen reviews 12,13,14,15,16,17,21,26,28,30,32,33,34,35,36,38,39,40 (including three Cochrane reviews) focused on the role of any form of fluorides (professionally applied, self‐applied, or fluoride‐releasing materials), and two other reviews 22,25 focused on the role of fluorides with calcium phosphopeptide‐amorphous calcium phosphate (CPP‐ACP). Three reviews 30,32,34 focused specifically on the role of fluoride varnishes, whereas one review focused on the role of professionally applied topical fluorides 35 .…”

“…Only 5 reviews 11,13,14,38,39 included in this overview were assessed by the authors to be of low risk of overall bias, whereas 23 reviews (equal to 24 published papers) 12,15,16,17,18,19,20,21,22,23,25,26,27,28,29,30,31,32,33,34,35,36,37,40 were assessed to be of high risk of overall bias, and one review 24 was of unclear risk of bias. The most common domain assessed to be of high risk or unclear risk was domain 1 (study eligibility criteria; 86.2%), followed by domains 2 and 3 (identification and selection of studies and data collection and study appraisal, respectively) with 51.7% of the reviews having high or unclear risk.…”

“…The summary of the 29 included reviews (30 published papers) is presented in Table 1. Three of the included reviews 12,14,15 were Cochrane reviews, of which two reviews 14,15 were the updates of the Cochrane review published in 2004 12 . Ten of the non‐Cochrane reviews had their protocols registered at PROSPERO, which were accessible for additional information 12,22,25,28,30,35,36,37,38,40 .…”

Prevention of demineralization during multi‐bracketed fixed orthodontic treatment: An overview of systematic reviews

“…One author of the conference abstract was contacted by email to obtain complete information about the systematic review, but no information could be obtained. Finally, 29 reviews (equal to 30 published papers 11‐40 ; since two of the papers 12,13 were almost identical, they were considered only once) met the eligibility criteria and were included in the present overview. The value of Cohen’s kappa for final inclusion after full‐text reading of the 86 articles among two reviewers (SD and MS) was found to be 0.85, indicating substantial agreement.…”

“…Three of the included reviews 12,14,15 were Cochrane reviews, of which two reviews 14,15 were the updates of the Cochrane review published in 2004 12 . Ten of the non‐Cochrane reviews had their protocols registered at PROSPERO, which were accessible for additional information 12,22,25,28,30,35,36,37,38,40 . Although Cochrane reviews are updated regularly, and the most updated review should be considered for making clinical decisions, the two older versions of the Cochrane reviews 12,14 were included as they are freely available online for the clinicians to make their clinical decisions.…”

“…Eighteen reviews 12,13,14,15,16,17,21,26,28,30,32,33,34,35,36,38,39,40 (including three Cochrane reviews) focused on the role of any form of fluorides (professionally applied, self‐applied, or fluoride‐releasing materials), and two other reviews 22,25 focused on the role of fluorides with calcium phosphopeptide‐amorphous calcium phosphate (CPP‐ACP). Three reviews 30,32,34 focused specifically on the role of fluoride varnishes, whereas one review focused on the role of professionally applied topical fluorides 35 .…”

“…Only 5 reviews 11,13,14,38,39 included in this overview were assessed by the authors to be of low risk of overall bias, whereas 23 reviews (equal to 24 published papers) 12,15,16,17,18,19,20,21,22,23,25,26,27,28,29,30,31,32,33,34,35,36,37,40 were assessed to be of high risk of overall bias, and one review 24 was of unclear risk of bias. The most common domain assessed to be of high risk or unclear risk was domain 1 (study eligibility criteria; 86.2%), followed by domains 2 and 3 (identification and selection of studies and data collection and study appraisal, respectively) with 51.7% of the reviews having high or unclear risk.…”

“…The summary of the 29 included reviews (30 published papers) is presented in Table 1. Three of the included reviews 12,14,15 were Cochrane reviews, of which two reviews 14,15 were the updates of the Cochrane review published in 2004 12 . Ten of the non‐Cochrane reviews had their protocols registered at PROSPERO, which were accessible for additional information 12,22,25,28,30,35,36,37,38,40 .…”

Prevention of demineralization during multi‐bracketed fixed orthodontic treatment: An overview of systematic reviews

“…One author of the conference abstract was contacted by email to obtain complete information about the systematic review, but no information could be obtained. Finally, 29 reviews (equal to 30 published papers 11‐40 ; since two of the papers 12,13 were almost identical, they were considered only once) met the eligibility criteria and were included in the present overview. The value of Cohen’s kappa for final inclusion after full‐text reading of the 86 articles among two reviewers (SD and MS) was found to be 0.85, indicating substantial agreement.…”

“…Three of the included reviews 12,14,15 were Cochrane reviews, of which two reviews 14,15 were the updates of the Cochrane review published in 2004 12 . Ten of the non‐Cochrane reviews had their protocols registered at PROSPERO, which were accessible for additional information 12,22,25,28,30,35,36,37,38,40 . Although Cochrane reviews are updated regularly, and the most updated review should be considered for making clinical decisions, the two older versions of the Cochrane reviews 12,14 were included as they are freely available online for the clinicians to make their clinical decisions.…”

“…Eighteen reviews 12,13,14,15,16,17,21,26,28,30,32,33,34,35,36,38,39,40 (including three Cochrane reviews) focused on the role of any form of fluorides (professionally applied, self‐applied, or fluoride‐releasing materials), and two other reviews 22,25 focused on the role of fluorides with calcium phosphopeptide‐amorphous calcium phosphate (CPP‐ACP). Three reviews 30,32,34 focused specifically on the role of fluoride varnishes, whereas one review focused on the role of professionally applied topical fluorides 35 .…”

“…Only 5 reviews 11,13,14,38,39 included in this overview were assessed by the authors to be of low risk of overall bias, whereas 23 reviews (equal to 24 published papers) 12,15,16,17,18,19,20,21,22,23,25,26,27,28,29,30,31,32,33,34,35,36,37,40 were assessed to be of high risk of overall bias, and one review 24 was of unclear risk of bias. The most common domain assessed to be of high risk or unclear risk was domain 1 (study eligibility criteria; 86.2%), followed by domains 2 and 3 (identification and selection of studies and data collection and study appraisal, respectively) with 51.7% of the reviews having high or unclear risk.…”

“…The summary of the 29 included reviews (30 published papers) is presented in Table 1. Three of the included reviews 12,14,15 were Cochrane reviews, of which two reviews 14,15 were the updates of the Cochrane review published in 2004 12 . Ten of the non‐Cochrane reviews had their protocols registered at PROSPERO, which were accessible for additional information 12,22,25,28,30,35,36,37,38,40 .…”