Fluid restriction for term infants with hypoxic-ischaemic encephalopathy following perinatal asphyxia

Hypoxic-Ischemic Encephalopathy

“…To limit the consequences of HIE, experts recommend carefully managing fluid therapy to avoid fluid overload and thus prevent cerebral edema. 33 Recommendations for neonatal fluid restriction are based on the experience of restricting fluid intake in adults and older children with cerebral edema to a target of 40 to 70 mL/kg/d. 33 In normal conditions, the human brain relies almost entirely on glucose to provide the substrate for metabolism.…”

“…33 Recommendations for neonatal fluid restriction are based on the experience of restricting fluid intake in adults and older children with cerebral edema to a target of 40 to 70 mL/kg/d. 33 In normal conditions, the human brain relies almost entirely on glucose to provide the substrate for metabolism. 34 Neonatal cerebral glucose consumption may account for 70% of total glucose consumption.…”

Hypoxic-Ischemic Encephalopathy

“…To limit the consequences of HIE, experts recommend carefully managing fluid therapy to avoid fluid overload and thus prevent cerebral edema. 33 Recommendations for neonatal fluid restriction are based on the experience of restricting fluid intake in adults and older children with cerebral edema to a target of 40 to 70 mL/kg/d. 33 In normal conditions, the human brain relies almost entirely on glucose to provide the substrate for metabolism.…”

“…33 Recommendations for neonatal fluid restriction are based on the experience of restricting fluid intake in adults and older children with cerebral edema to a target of 40 to 70 mL/kg/d. 33 In normal conditions, the human brain relies almost entirely on glucose to provide the substrate for metabolism. 34 Neonatal cerebral glucose consumption may account for 70% of total glucose consumption.…”

Hypoxic-Ischemic Encephalopathy in Neonates Born to Severe Birth Asphyxia

“…Инфузионная терапия должна быть индивиду-альной и подбираться на основании: тяжести и тече-ния ГИЭ; определения концентрации электролитов и глюкозы; динамики веса; исследования почечной функции [31]. Эпизоды гипогликемии и гипергли-кемии могут усилить повреждения головного мозга [4], в связи с чем необходим тщательный контроль глюкозы крови.…”

Management of neonatal hazards in intensive care units: a review

“…Because of the concern for acute tubular necrosis and syndrome of inappropriate antidiuretic hormone secretion, fluid restriction is typically recommended for these infants until renal function and urine output can be evaluated. 98 Hyperthermia has been shown to be associated with increased risk of adverse outcomes in neonates with moderate-to-severe hypoxicischemic encephalopathy. 99 Hypoxic-ischemic encephalopathy is the most common cause of seizures in the neonatal period.…”

Hypoxic-Ischemic Encephalopathy

“…To limit the consequences of HIE, experts recommend carefully managing fluid therapy to avoid fluid overload and thus prevent cerebral edema. 33 Recommendations for neonatal fluid restriction are based on the experience of restricting fluid intake in adults and older children with cerebral edema to a target of 40 to 70 mL/kg/d. 33 In normal conditions, the human brain relies almost entirely on glucose to provide the substrate for metabolism.…”

“…33 Recommendations for neonatal fluid restriction are based on the experience of restricting fluid intake in adults and older children with cerebral edema to a target of 40 to 70 mL/kg/d. 33 In normal conditions, the human brain relies almost entirely on glucose to provide the substrate for metabolism. 34 Neonatal cerebral glucose consumption may account for 70% of total glucose consumption.…”

Hypoxic-Ischemic Encephalopathy in Neonates Born to Severe Birth Asphyxia

“…Инфузионная терапия должна быть индивиду-альной и подбираться на основании: тяжести и тече-ния ГИЭ; определения концентрации электролитов и глюкозы; динамики веса; исследования почечной функции [31]. Эпизоды гипогликемии и гипергли-кемии могут усилить повреждения головного мозга [4], в связи с чем необходим тщательный контроль глюкозы крови.…”

Management of neonatal hazards in intensive care units: a review

“…Because of the concern for acute tubular necrosis and syndrome of inappropriate antidiuretic hormone secretion, fluid restriction is typically recommended for these infants until renal function and urine output can be evaluated. 98 Hyperthermia has been shown to be associated with increased risk of adverse outcomes in neonates with moderate-to-severe hypoxicischemic encephalopathy. 99 Hypoxic-ischemic encephalopathy is the most common cause of seizures in the neonatal period.…”

Hypoxic-Ischemic Encephalopathy

“…To limit the consequences of HIE, experts recommend carefully managing fluid therapy to avoid fluid overload and thus prevent cerebral edema. 33 Recommendations for neonatal fluid restriction are based on the experience of restricting fluid intake in adults and older children with cerebral edema to a target of 40 to 70 mL/kg/d. 33 In normal conditions, the human brain relies almost entirely on glucose to provide the substrate for metabolism.…”

“…33 Recommendations for neonatal fluid restriction are based on the experience of restricting fluid intake in adults and older children with cerebral edema to a target of 40 to 70 mL/kg/d. 33 In normal conditions, the human brain relies almost entirely on glucose to provide the substrate for metabolism. 34 Neonatal cerebral glucose consumption may account for 70% of total glucose consumption.…”

Hypoxic-Ischemic Encephalopathy in Neonates Born to Severe Birth Asphyxia

“…Инфузионная терапия должна быть индивиду-альной и подбираться на основании: тяжести и тече-ния ГИЭ; определения концентрации электролитов и глюкозы; динамики веса; исследования почечной функции [31]. Эпизоды гипогликемии и гипергли-кемии могут усилить повреждения головного мозга [4], в связи с чем необходим тщательный контроль глюкозы крови.…”

Management of neonatal hazards in intensive care units: a review

“…Because of the concern for acute tubular necrosis and syndrome of inappropriate antidiuretic hormone secretion, fluid restriction is typically recommended for these infants until renal function and urine output can be evaluated. 98 Hyperthermia has been shown to be associated with increased risk of adverse outcomes in neonates with moderate-to-severe hypoxicischemic encephalopathy. 99 Hypoxic-ischemic encephalopathy is the most common cause of seizures in the neonatal period.…”