Fluid, Electrolyte, and Renal Indices of Hydration during 11 Days of Controlled Caffeine Consumption

Armstrong, Lawrence E.; Pumerantz, Amy C.; Roti, Melissa W.; Judelson, Daniel A.; Watson, Greig; Dias, João Carlos Teixeira; Sökmen, Bülent; Casa, Douglas J.; Maresh, Carl M.; Lieberman, Harris R.; Kellogg, Mark D.

doi:10.1123/ijsnem.15.3.252

Cited by 102 publications

(70 citation statements)

References 31 publications

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“…11,53 Although caffeine is a mild diuretic, consumption of Յ500 mg/day does not cause dehydration or chronic water imbalance. 54,55 Caffeine is a ventilatory stimulant with anti-inflammatory and bronchoprotective effects. 56 Caffeine has been linked to dyspnea on exertion from central and peripheral chemoreceptor stimulation.…”

Section: Figurementioning

confidence: 99%

Health Effects of Energy Drinks on Children, Adolescents, and Young Adults

et al. 2011

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"poison control center" to identify articles related to energy drinks. Manufacturer Web sites were reviewed for product information. RESULTS:According to self-report surveys, energy drinks are consumed by 30% to 50% of adolescents and young adults. Frequently containing high and unregulated amounts of caffeine, these drinks have been reported in association with serious adverse effects, especially in children, adolescents, and young adults with seizures, diabetes, cardiac abnormalities, or mood and behavioral disorders or those who take certain medications. Of the 5448 US caffeine overdoses reported in 2007, 46% occurred in those younger than 19 years. Several countries and states have debated or restricted energy drink sales and advertising. CONCLUSIONS:Energy drinks have no therapeutic benefit, and many ingredients are understudied and not regulated. The known and unknown pharmacology of agents included in such drinks, combined with reports of toxicity, raises concern for potentially serious adverse effects in association with energy drink use. In the short-term, pediatricians need to be aware of the possible effects of energy drinks in vulnerable populations and screen for consumption to educate families. Long-term research should aim to understand the effects in at-risk populations. Toxicity surveillance should be improved, and regulations of energy drink sales and consumption should be based on appropriate research.

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Section: Figurementioning

confidence: 99%

Health Effects of Energy Drinks on Children, Adolescents, and Young Adults

et al. 2011

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“…The available literature has shown that doses of more than about 250-300 mg caffeine (equivalent to 2-3 cups of coffee) have a mild diuretic effect, while doses of less than 250 mg do not show any effect. 57,58 Thus, doses of caffeine equivalent to the amount normally found in standard servings of tea, coffee and carbonated soft drinks appear to have no diuretic action. 57 In contrast, alcohol has a more potent diuretic effect and 1 gram is sufficient to increase urine output by 10 ml.…”

Section: Discussionmentioning

confidence: 99%

Alcohol consumption and risk of bladder cancer in Los Angeles County

Jiang

Castelao

Groshen

et al. 2007

Intl Journal of Cancer

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The role of alcoholic beverages in bladder carcinogenesis is still unclear, with conflicting evidence from different studies. We investigated the relationship between alcohol consumption and bladder cancer, and the potential interaction between alcohol consumption and other exposures. In a population-based case-control study conducted in Los Angeles County, 1,586 pairs of cases and their matched neighborhood controls were interviewed. Data were analyzed to determine whether bladder cancer risk differs by alcohol consumption, and whether different alcoholic beverages have different effects. The risk of bladder cancer decreased with increasing frequency (p for trend 5 0.003) and duration of alcohol consumption (p for trend 5 0.017). Subjects who drank more than 4 drinks per day had a 32% lower (odds ratio, 0.68; 95% confidence interval, 0.52-0.90) risk of bladder cancer than those who never drank any alcoholic beverage. Beer (p for trend 5 0.002) and wine (p for trend 5 0.054) consumption were associated with reduced risk of bladder cancer, while hard liquor was not. The reduction in risk was mostly seen among shorter-term smokers who urinated frequently. Alcohol consumption was strongly associated with a reduced risk of bladder cancer. The effect was modified by the type of alcoholic beverage, cigarette smoking and frequency of urination. ' 2007 Wiley-Liss, Inc.

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“…[5] Opposing this viewpoint, Armstrong [6] concluded that the diuretic effect of caffeine is overstated and further may be minimised for habitual caffeine consumers. In support of this view, Armstrong et al [7] provided strong evidence for no caffeine-induced diuresis (<500 mg/24 hours) in males undergoing daily activities with no strenuous physical training.…”

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confidence: 60%

Effect of caffeine ingestion on fluid balance during exercise in the heat and during recovery

et al. 2014

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Background. The effect of ingestion of a common stimulant, caffeine, on fluid balance during exercise and recovery is not fully known. Objectives. To determine the effect of caffeine on fluid balance during exercise in the heat and during a 3-hour recovery period thereafter. Methods. In a randomised, controlled design, caffeine-naive participants (N=8) pedalled on a bike to achieve 2.5% baseline body mass loss in a hot environment in four separate conditions: with (C+) or without (C-) caffeine ingestion (6 mg/kg of body mass) prior to exercise, followed by (W+) or without (W-) 100% fluid replenishment (water) of the body mass loss during a 3-hour recovery period (yielding C+W+, C+W-, C-W+ and C-W-, respectively). Results. Mean (standard deviation) urine production was not different (p>0.05) regardless of rehydration status: 230 (162) mL (C+W-) v. 168 (77) mL (C-W-); and 713 (201) mL (C+W+) v. 634 (185) mL (C-W+). For the 3-hour recovery, caffeine ingestion caused higher hypohydration during rehydration conditions (p=0.02), but practically the mean difference in the loss of body mass was only 0.2 kg. Conclusion. In practical terms, there was no evidence that caffeine ingestion in moderation would impair fluid balance during prolonged exercise in the heat or during 3 hours of recovery. Current military doctrine places operational forces in unique situations in which soldiers are often engaged in sustained activities to achieve mission objectives. Since modern military operations are both physically and cognitively demanding, and recovery can often be inadequate, there has been an increased interest in caffeine as an effective dietary supplement to counter performance deficits S Afr J SM

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Fluid, Electrolyte, and Renal Indices of Hydration during 11 Days of Controlled Caffeine Consumption

Cited by 102 publications

References 31 publications

Health Effects of Energy Drinks on Children, Adolescents, and Young Adults

Health Effects of Energy Drinks on Children, Adolescents, and Young Adults

Alcohol consumption and risk of bladder cancer in Los Angeles County

Effect of caffeine ingestion on fluid balance during exercise in the heat and during recovery

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