Flower-like gold nanostructures electrodeposited on indium tin oxide (ITO) glass as a SERS-active substrate for sensing dopamine

Abstract

Flower-like gold nanostructures (so called gold nanoflowers) were electrodeposited on indium tine oxide (ITO) glass and served as a SERS-active substrate for sensing dopamine. A double-potential method was applied for the deposition of gold nanostructures on the glass. The density, size, and morphology of the gold nanostructures were controlled by adjusting parameters such as deposition potentials, duration, and concentrations of gold precursors. The particle density on the glass was controlled by changing the overvoltage potentials, while the size and morphology were controlled by changing the concentration of gold precursors and growth times of Gold crystal seeds. The intensity of the Raman spectrum of dopamine was distinctly enhanced on the gold nanostructures with unique flower-like topography, thereby demonstrating the utility of this SERS-active substrate that is facilely obtained by the double-potential deposition method without supporting electrolytes.

Sandwiching analytes with structurally diverse plasmonic nanoparticles on paper substrates for surface enhanced Raman spectroscopy

“…A droplet of NP solution on the glass slides took a long time to dry and visually formed a ring by random aggregation (e.g., NP-dependent irregular surface coverage and coffee ring patterns to show inhomogeneous distribution), which were certainly different from the controlled assembly and packing of NPs on surface-modied glass substrates. [62][63][64][65][66] Given the heterogeneous loading of the NPs, the overall SERS responses were slightly weaker and notably inconsistent across the glass substrates. Specically, the signal intensity at the edge was much higher than the center of the droplet regardless of NP types, giving notably high % RSD (Fig.…”

Biosensor Applications of Electrodeposited Nanostructures

“…Flower-shaped gold nanostructures were formed by electrodeposition onto silanized ITO-coated glass electrodes, and found to be sensitive substrates for the detection of dopamine by surface-enhanced Raman spectroscopy [90]. The ITO-coated glass was first silanized with a monolayer of aminopropyltrimethoxysilane followed by electrodeposition using a two-second nucleation step at 0.7 V (versus SCE) followed by 600 s at −0.4 V from 0.5 to 1.0 mM of HAuCl 4 .…”

Sensitive determination of dopamine levels via surface-enhanced Raman scattering of Ag nanoparticle dimers

“…17,19 In recent years, various nanostructures have been used for SERS detection in DA molecules. 20 An LOD of 1.05 pM DA level has been obtained by using an Ag/MIL-101 nanostructure, 11 an LOD of 0.1 mM by using flower-like gold nanostructures electrodeposited on indium tin oxide glass, 13,20 an LOD of 1 nM with graphene-Au nanopyramid heterostructure, 13 and an LOD of 0.006 pM has been achieved with Au@Ag nanorod dimers. 18 Meanwhile, efforts have been made for the quantitative analysis of DA.…”