Flip-Top Pigment Transplantation

McGovern, Thomas W.; Bolognia, Jean L.; Leffell, David J.

doi:10.1001/archderm.135.11.1305

Cited by 33 publications

(8 citation statements)

References 21 publications

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“…Recently a novel split-thickness graft technique has been described by McGovern et al [24]. They developed a flip-top pigment transplantation procedure.…”

Section: Split Thickness Graftsmentioning

confidence: 99%

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Surgical Techniques for Vitiligo: A Review

Geel

Ongenae

Naeyaert³

2001

Dermatology

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Although the treatment of vitiligo has improved during the last decade, therapy is still not satisfying for many patients. This is probably due to the fact that the aetiopathogenesis is unknown. Several treatment modalities, such as PUVA, UVB and local corticosteroids are currently used in the treatment of active vitiligo. However, these treatments usually induce incomplete repigmentation. Surgical methods intended to repigment leucoderma are an interesting therapeutic option if patients have stable disease. Two types of surgical techniques are available: tissue grafts and cellular grafts, with in between autologous cultured epithelial grafts. Tissue grafts are full-thickness punch grafts, split-thickness grafts and suction blister grafts. With tissue grafts, only a limited surface area can be treated but with good results in the majority of cases. Cellular grafts include non-cultured keratinocytes/melanocytes and cultured melanocytes. The exact success rate of repigmentation with cellular grafts is still unknown, since only a small number of studies have been published. Starting from autologous cellular suspensions, epithelial grafts of various compositions can be cultured in vitro. They can be used for larger areas. The purpose of this review is to describe the applications of different surgical techniques used to treat recalcitrant vitiligo.

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“…Recently a novel split-thickness graft technique has been described by McGovern et al [24]. They developed a flip-top pigment transplantation procedure.…”

Section: Split Thickness Graftsmentioning

confidence: 99%

“…After 1 week the dressing was removed. Success was seen in 88% of 25 grafts in 4 patients and no visible scarring occurred [24]. …”

Section: Split Thickness Graftsmentioning

confidence: 99%

Surgical Techniques for Vitiligo: A Review

Geel

Ongenae

Naeyaert³

2001

Dermatology

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“…Before the cellular transplantation procedures were being popularized, this method had been reported as the most effective surgical method. [10] In flip-top grafting (1999), [11] small pieces of epidermal grafts are placed under a hinge of raised epidermal flaps, which act as a natural dressing. The success of graft can be ascertained by observing the pigmentation through the depigmented epidermal hinge.…”

Section: Tissue G R Af Tsmentioning

confidence: 99%

Vitiligo surgery: A journey from tissues via cells to the stems!

Afra

Parsad

2018

Experimental Dermatology

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Depigmented patches in vitiligo, a common dermatosis, cause a great psychological distress to the patients. Hence, apart from halting the disease process, the strategies to impart normal skin colour to these white patches carry an important role in the management of vitiligo. Surgical procedures are often required for stable vitiligo lesions not responding to medical therapies. It involves “shuffling” of melanocytes from the pigmented skin to the depigmented areas. During the last fifty years, the vitiligo surgery has evolved from tissue transplantation via cellular transplantation to reach a stage where the use of stem cells or immunomodulatory cells is contemplating. We would like to depict this wonderful journey of vitiligo surgery through this viewpoint.

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“…Occasionally, the donor area too can develop scar and keloid formation (10,184). McGovern et al (185) have described a flip-top pigment transplantation procedure, and found an 88% success rate amongst 25 grafts from four patients.…”

Section: Split Thickness Graftingmentioning

confidence: 99%

Vitiligo treatment options: An evolving scenario

Sehgal¹,

Srivastava²

2006

Journal of Dermatological Treatment

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Sequential displays of several treatment options for vitiligo have been scanned from the literature, and are presented here. A few of the medical modalities have been resigned to history, whereas others have become customary in clinical practice. There has also been a recent surge of interest in the surgical treatment of this disease. Accordingly, this has been appraised and summarized. Special attention has been given to prevalent medical modalities so that they may be effectively utilized by those currently in practice.

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Flip-Top Pigment Transplantation

Cited by 33 publications

References 21 publications

Surgical Techniques for Vitiligo: A Review

Surgical Techniques for Vitiligo: A Review

Vitiligo surgery: A journey from tissues via cells to the stems!

Vitiligo treatment options: An evolving scenario

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