Flecked Retina Syndrome

Functional and morphological variations of fundus flavimaculatus

“…In four of our five cases we found a delay of rod-cone transition in the dark adaptation function with normal final threshold, similar to cases described by Krill and Klien (1965) and Klien and Krill (1967). In contrast, Patient 5 had a totally normal course of dark adaptation with a slightly elevated final rod threshold, as shown in Fig.…”

“…His blue-cone spectral sensitivity as well as the function of transient tritanopia were reduced, while the other four cases were normal. His dark adaptation curve was almost normal while the cone-rod transition of the others was delayed, as also described by Krill and Klien (1965) and Klien and Krill (1967) in 22 of 23 patients with fundus flavimaculatus. All the results obtained by these psychophysical tests are different from the findings in the four other patients.…”

Functional and morphological variations of fundus flavimaculatus

“…In four of our five cases we found a delay of rod-cone transition in the dark adaptation function with normal final threshold, similar to cases described by Krill and Klien (1965) and Klien and Krill (1967). In contrast, Patient 5 had a totally normal course of dark adaptation with a slightly elevated final rod threshold, as shown in Fig.…”

“…His blue-cone spectral sensitivity as well as the function of transient tritanopia were reduced, while the other four cases were normal. His dark adaptation curve was almost normal while the cone-rod transition of the others was delayed, as also described by Krill and Klien (1965) and Klien and Krill (1967) in 22 of 23 patients with fundus flavimaculatus. All the results obtained by these psychophysical tests are different from the findings in the four other patients.…”

Stargardt's disease

“…The ERG examination is usually normal [8,16,19,20,24,34], but occasionally, slight reductions in the photopic and scotopic responses have been reported [3,4,6,21,26,35,37,39]. Only one of our patients showed decreased responses both in the photopic and scotopic ERG.…”

Calcium Oxalate Crystals Localized in the Eye

“…They found the crystals in the retina, but also for the first time in the pigment epithelium as seen light microscopically and ultrastructurally. These writers were able to associate the histopathological findings with the clinical picture of the "flecked retina syndrome" of Krill & Klien (1965), a fundus picture with presumably several aetiologies of which oxalate crystal deposition may be only one. Furthermore, these writers demonstrated a connection with methoxyflurane anaesthesia.…”

Functional and morphological variations of fundus flavimaculatus

“…In four of our five cases we found a delay of rod-cone transition in the dark adaptation function with normal final threshold, similar to cases described by Krill and Klien (1965) and Klien and Krill (1967). In contrast, Patient 5 had a totally normal course of dark adaptation with a slightly elevated final rod threshold, as shown in Fig.…”

“…His blue-cone spectral sensitivity as well as the function of transient tritanopia were reduced, while the other four cases were normal. His dark adaptation curve was almost normal while the cone-rod transition of the others was delayed, as also described by Krill and Klien (1965) and Klien and Krill (1967) in 22 of 23 patients with fundus flavimaculatus. All the results obtained by these psychophysical tests are different from the findings in the four other patients.…”

Stargardt's disease

“…The ERG examination is usually normal [8,16,19,20,24,34], but occasionally, slight reductions in the photopic and scotopic responses have been reported [3,4,6,21,26,35,37,39]. Only one of our patients showed decreased responses both in the photopic and scotopic ERG.…”

Calcium Oxalate Crystals Localized in the Eye

“…They found the crystals in the retina, but also for the first time in the pigment epithelium as seen light microscopically and ultrastructurally. These writers were able to associate the histopathological findings with the clinical picture of the "flecked retina syndrome" of Krill & Klien (1965), a fundus picture with presumably several aetiologies of which oxalate crystal deposition may be only one. Furthermore, these writers demonstrated a connection with methoxyflurane anaesthesia.…”

Functional and morphological variations of fundus flavimaculatus

“…In four of our five cases we found a delay of rod-cone transition in the dark adaptation function with normal final threshold, similar to cases described by Krill and Klien (1965) and Klien and Krill (1967). In contrast, Patient 5 had a totally normal course of dark adaptation with a slightly elevated final rod threshold, as shown in Fig.…”

“…His blue-cone spectral sensitivity as well as the function of transient tritanopia were reduced, while the other four cases were normal. His dark adaptation curve was almost normal while the cone-rod transition of the others was delayed, as also described by Krill and Klien (1965) and Klien and Krill (1967) in 22 of 23 patients with fundus flavimaculatus. All the results obtained by these psychophysical tests are different from the findings in the four other patients.…”

Stargardt's disease

“…The ERG examination is usually normal [8,16,19,20,24,34], but occasionally, slight reductions in the photopic and scotopic responses have been reported [3,4,6,21,26,35,37,39]. Only one of our patients showed decreased responses both in the photopic and scotopic ERG.…”

Calcium Oxalate Crystals Localized in the Eye

“…They found the crystals in the retina, but also for the first time in the pigment epithelium as seen light microscopically and ultrastructurally. These writers were able to associate the histopathological findings with the clinical picture of the "flecked retina syndrome" of Krill & Klien (1965), a fundus picture with presumably several aetiologies of which oxalate crystal deposition may be only one. Furthermore, these writers demonstrated a connection with methoxyflurane anaesthesia.…”