Flavonoids and other phenolics from Artemisia hispanica

Anti-inflammatory and immunosuppressive effect of flavones isolated from Artemisia vestita

“…and activation by cirsilineol, apigenin and 6-methoxytricin. Considering that the three flavones had been isolated previously from Artemisia genus plants such as Artemisia judaica (Saleh et al, 1987), Artemisia hispanica (Macro et al, 1988) and Artemisia scoparia (Zhang et al, 2002), and that the plants of this genus have shown the anti-inflammatory and anti-tumor activities (Tan et al, 1998), we inferred that cirsilineol, apigenin and 6-methoxytricin might be the common chemical substances among the plants of this genus and were responsible for immunosuppressive and anti-inflammatory activities.…”

Biological activity of new flavonoid from Hieracium pilosella L.

“…Mass spectra showed quasimolecular ion peaks [ [16,18] showed the glycosylation in the B-ring led to a hypsochromic shift to shorter wavelengths in band I in relation to aglycone spectrum suggesting a flavone which is glycosylated in the B-ring. In the spectrum after the addition of NaOAc, the hypsochromic shift in relation to aglycone spectrum was observed and pointed out the B-ring glycosylation as well [17,18]. There was neither a bathochromic effect in the NaOAc/H 3 BO 3 spectrum nor a hypsochromic effect in the AlCl 3 /HCl spectrum (towards the AlCl 3 spectrum) because free 4',5' (ortho)-dihydroxy groups were lacking [22].…”

“…On the other hand hawkweed contains many phenolic compounds with phytotoxic properties which are responsible for its strong allelopathic potential. Until now eleven different glycosides of isoetin (hieracin, rare 5,7,2',4',5'-pentahydroxyflavone) have been identified in species mainly from the Asteraceae family, including representatives of Hieracium genus [14][15][16][17][18][19]. Two of them appeared to be good radical scavengers and another derivative (isoetin 5'-methyl ether) inhibited the proliferation of tumor cell cultures -human lung cancer cell line A549, human melanoma SK-Mel-2 and mouse melanoma B16F1 cell lines [20,21].…”

Assessment of microtubule depolymerization property of flavonoids isolated from Tanacetum gracile in breast cancer cells by biochemical and molecular docking approach

“…Thus, the structure of compound 1 was established as 5-hydro xy-3,6,7,3 0 ,4 0 -pentamethoxyflavone which was identical to that of artemetin [31]. Similar patterns of 2D NMR correlations, also established compound 2 as 5,4 0 -dihydrox y-3,6,7,3 0 ,4 0 -tetramethoxyflavone, identical to that of chrysosplenetin [32]. This is the first report of chrysosplenetin in T. gracile.…”