Fixed subaortic stenosis in the young: Medical and surgical course in 83 patients

Surgical Outcome of Discrete Subaortic Stenosis in Adults

“…[1][2][3][4][5][6][7] Different strategies exist for the timing of surgical treatment, ranging from early (mild to moderate obstruction) to late (severe or symptomatic) repair. Early repair has been advocated to prevent aortic valve damage and thus AR progression.…”

“…Early repair has been advocated to prevent aortic valve damage and thus AR progression. [5][6][7][8][9][10][11][12] Nevertheless, it remains unclear whether surgery can actually alter the course of progressive AR. Furthermore, surgery is associated with a high recurrence risk and need for reoperation (8%-34%).…”

Short- and mid-term results of resection of discrete subaortic stenosis in children

“…Genetic, congenital, inflammatory, and acquired causes are usually held responsible for the development of this entity. [4,9] Although the idea of the acquired nature of the disease has gained popularity in recent years, since the disease is not present at birth but it develops and progresses afterwards, the presence of some familiar cases has suggested that it may also have a genetic etiology. [5] The LVOT gradient is a surgical indication; however, many patients are asymptomatic.…”

“…[3,4] Progressively increasing aortic valve regurgitation due to the presence of stenosis also increases the risk for infective endocarditis. [7,12,13] Therefore, the timing of surgery should be planned in patients with discrete subaortic membrane, considering the gradient in the LVOT and progression of the aortic regurgitation.…”

“…[1,2] Discrete subaortic stenosis may lead to left ventricular hypertrophy and regurgitation, as well as arrhythmias, aortic valve regurgitation, and endocarditis. [3,4] Although surgical treatment is recognized as an effective method of treatment, the rates of recurrence of stenosis and requirement of reoperation have been reported to be up to 50% with varying figures according to the results from two studies [5,6] In this study, we report our short and mid-term surgical results in patients with discrete subaortic stenosis.…”