1999
DOI: 10.1080/003655299750025877
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Abstract: Combined 24-h pH-manometry has been shown to be a useful and cost-effective test for the management of selected patients in whom the primary investigation was insufficient.

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Cited by 20 publications
(2 citation statements)
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References 43 publications
(59 reference statements)
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“…Patients with the main complaint of NCCP were less likely to have GERD (LR + 0.83, 0.43; LR- 1.13, 1.23) compared to patients with the main complaint of dysphagia (LR + 1.27, 1.16; LR- 0.97, 0.97) or GERD typical symptoms without chest pain (LR + 1.26, 1.53; LR- 0.93, 0.74) in two studies [25,26]. Two further studies compared the accuracy of NCCP and typical GERD symptoms (LR + 2.70 [27], 2.75 [24]; LR- 0.42 [24], 0.78 [27]) with NCCP without GERD symptoms (LR + 0.49; LR- 2.71 [24]) or with NCCP and a history of heart burn (LR + 2.15; LR- 0.74 [27]).…”
Section: Resultsmentioning
confidence: 99%
“…Patients with the main complaint of NCCP were less likely to have GERD (LR + 0.83, 0.43; LR- 1.13, 1.23) compared to patients with the main complaint of dysphagia (LR + 1.27, 1.16; LR- 0.97, 0.97) or GERD typical symptoms without chest pain (LR + 1.26, 1.53; LR- 0.93, 0.74) in two studies [25,26]. Two further studies compared the accuracy of NCCP and typical GERD symptoms (LR + 2.70 [27], 2.75 [24]; LR- 0.42 [24], 0.78 [27]) with NCCP without GERD symptoms (LR + 0.49; LR- 2.71 [24]) or with NCCP and a history of heart burn (LR + 2.15; LR- 0.74 [27]).…”
Section: Resultsmentioning
confidence: 99%
“…By contrast, Hong et al [21] divided 462 patients into 4 symptom categories (dysphagia, noncardiac chest pain, gastroesophageal reflux disease-related, and extraesophageal symptoms) and stated that these categories are helpful in predicting the likelihood of abnormal manometric findings. A review of 315 consecutive patients who were evaluated with both 24-hour pH monitoring and 24-hour ambulatory manometry over a 5-year period found that manometry altered the diagnosis of 44% of these patients and changed the management of 66% of these patients [22]. Similarly, Lacy et al [23] reported that among 286 consecutive patients, new information was obtained in 87%, whereas a change in diagnosis occurred in 30% and in management in 44% of the patients after manometry.…”
Section: Discussionmentioning
confidence: 99%