Neutral Particle Analyzer (NPA) is one of the crucial diagnostic devices on Tokamak facilities. Stripping unit is one of the main parts of the NPA. A windowless gas stripping room with two differential pipes is adopted in a parallel direction of electric and magnetic fields (E//B) NPA. The pressure distributions in the stripping chamber are simulated by Ansys Fluent together with MolFlow+. Based on the pressure distributions extracted from the simulation, the stripping efficiency of the E//B NPA is studied with GEANT4. The hadron reaction physics is modified to track the charge state of each particle in a cross section base method in GEANT4. The transmission rates (R) and the stripping efficiencies f+1 are examined for the particle energy ranging from 20 to 200 keV at the input pressure (P0) ranging from 20 to 400 Pa. According to the combined global efficiency, R × f+1, P0 = 240 Pa is obtained as the optimum pressure for the maximum global efficiency in the incident energy range investigated.