Fireflies‐On‐A‐Chip: (Ionic Liquid)–Aqueous Microdroplets for Biphasic Chemical Analysis

Abstract

Inspired by the enchanting bioluminescence of fireflies, herein microfluidic droplet‐based ‘fireflies’ for non‐invasive biphasic chemical analysis are demonstrated. Bicompartmental droplets are created where a model analyte is transported from the aqueous compartment to the adjacent ionic liquid segment, yielding a bright fluid firefly structure via a localized catalytic reaction. Analysis of fluorescence emission kinetics and a method to passively decouple the two compartments at a constriction are presented.

Wetting-induced formation of controllable monodisperse multiple emulsions in microfluidics

“…Control of the spreading coefficients of immiscible phases has been used to create a wide variety of shapes by causing partial wetting of the interface. [24][25][26] Here we ensure that the wetting of immiscible drops is complete, causing the outer drop to fully engulf the inner drop to form a multiple emulsion.…”

Nanocatalosomes as Plasmonic Bilayer Shells with Interlayer Catalytic Nanospaces for Solar‐Light‐Induced Reactions

“…Au‐based catalysts have special place in organic synthesis due their selective affinity towards coordination with alkyne‐group in the presence of other functional groups, resulting a number of unique molecular transformations useful in pharmaceutical synthesis and biorthogonal chemistry; however, most of these alkyne‐activation‐based chemistries are only possible with non‐recyclable homogeneous Au I/III ‐complexes with only very few examples of AuNP‐based recyclable green catalysts showing low reactivity . With the use of metal‐bilayer structure of Au‐1–4‐NCat and by harnessing the interlayer plasmonic‐catalytic nanocavities for catalysis, we envisioned to compensate the low reactivity of [Au]‐catalyzed alkyne‐activation.…”

Micro Total Analysis Systems: Fundamental Advances and Applications in the Laboratory, Clinic, and Field

“…(b) Bicompartmental droplets allowed analyte transport into an ionic liquid droplet to produce a fluorescent product that could be decoupled from the combined droplets. From ref 93. Copyright 2012 John Wiley & Sons, Inc. (c) A microfluidic device for combinatorial synthesis by droplet fusion utilized multiple droplet injection regions and electrocoalescence-based droplet fusion.…”