Fine needle aspiration cytology of an acral myxoinflammatory fibroblastic sarcoma: case report with cytological and cytogenetic findings

González‐Cámpora, Ricardo; Ríos-Martín, Juan José; Solórzano-Amoretti, A; Monteros, M T Vargas de los; Trigo-Sánchez, I; Otal-Salaverri, C; Galera-Davidson, H

doi:10.1111/j.1365-2303.2006.00420.x

Cited by 19 publications

(15 citation statements)

References 17 publications

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“…Regarding tumour location, initial reports overemphasised the predilection for distal extremities, so the term acral myxoinflammatory fibroblastic sarcoma was coined [2]. Although the adjective acral was deleted from the official nomenclature in 2002 because some cases are located axially [3], its use is still common [19,20,26,28,29,32,34,36,39,45]. Our analysis confirms that distal extremities are involved in the majority of cases, with hands and fingers being the most common sites.…”

Section: Discussionsupporting

confidence: 70%

A case of lung metastasis in myxoinflammatory fibroblastic sarcoma: analytical review of one hundred and thirty eight cases

Lombardi

Jovine

Zanini

et al. 2013

International Orthopaedics (SICOT)

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Purpose Myxoinflammatory fibroblastic sarcoma (MIFS) is a rare soft tissue tumour first identified at the end of the 1990s. This study presents our experience and literature reviews focusing on risk of recurrence. Methods Rizzoli Orthopaedic Institute database and literature were searched for patients with MIFS observed from 1997 to 2012. Data were analysed in a new database. Results Five patients underwent surgery at our institute, and 133 cases were retrieved from the literature. Not all clinicopathological data were available: 76/138 were men (55 %), median age was 45 [interquartile range (IQR) 34-56] years, median tumour size was three (IQR two to five) centimetres. Common sites of occurrence were hand (24 %), fingers (23 %) and foot (20 %). Pain was present at diagnosis in 14/82 patients (17 %), with a median duration of seven (IQR three to 12) months. Surgery was performed for a suspected benign tumour in 88 patients (74 %). Resection was incomplete in 45/ 71 cases (63 %); re-excision was performed in 32/45 (71 %). At a median follow-up of 26 months, 26/118 patients (22 %) developed recurrent disease; median time to recurrence was 15 months (IQR seven to 26). Actuarial relapse-free survival (RFS) at one, three and five years was 93 %, 72 % and 67 %, respectively. At univariate analysis, only symptom duration of six months or less was significantly associated with a worse RFS (p=0.046). Metastatic disease to lymph nodes and/or lungs was observed in four patients (3 %). Conclusions Clinicopathological findings confirm the lowgrade nature of MIFS. However, local recurrence occurs, and patients may be affected by aggressive forms with a potential for distant metastases. Follow-up is strongly advised.

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Section: Discussionsupporting

confidence: 70%

A case of lung metastasis in myxoinflammatory fibroblastic sarcoma: analytical review of one hundred and thirty eight cases

Lombardi

Jovine

Zanini

et al. 2013

International Orthopaedics (SICOT)

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“…A review of the orthopedic international literature shows that there are only a few reported cases [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20].…”

Section: Introductionmentioning

confidence: 99%

A rare case of acral myxoinflammatory fibroblastic sarcoma at the hand

2010

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One case of acral myxoinflammatory fibroblastic sarcoma is presented. Most of the soft tissue tumefactions of the distal extremities are benign. Sarcomas are rare and usually high grade. Acral myxoinflammatory fibroblastic sarcoma is a unique low-grade tumor described by Kindblom in 1998. This neoplasm has a propensity for digits, presents a low rate of metastasis and is characterized by a high rate of local multiple and aggressive recurrence. The clinical presentation, the frequent association with tenosynovitis and the extensive inflammatory infiltrate can lead to misdiagnosis by both the surgeon and the pathologist. Correct and early diagnosis depends on a good knowledge of histological and immunohistochemical findings. It is important to avoid recurrences recurring to an immediate wide excision of the tumor.

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“…Clonal chromosomal aberrations have been detected by cytogenetic analysis in 10 cases of MIFS and hybrid MIFS/hemosiderotic fibrolipomatous tumor (HFLT) (57)(58)(59)(60)(61)(62)(63). Cytogenetic and molecular cytogenetic studies have identified the frequent presence of a balanced or unbalanced t(1;10) (p22;q24) translocation and ring or marker chromosomes secondary to 3p11-12 amplifications.…”

Section: Intermediate Soft Tissue Tumorsmentioning

confidence: 99%

Updates on the cytogenetics and molecular cytogenetics of benign and intermediate soft tissue tumors

Nishio

2012

Oncology Letters

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Fine needle aspiration cytology of an acral myxoinflammatory fibroblastic sarcoma: case report with cytological and cytogenetic findings

Cited by 19 publications

References 17 publications

A case of lung metastasis in myxoinflammatory fibroblastic sarcoma: analytical review of one hundred and thirty eight cases

A case of lung metastasis in myxoinflammatory fibroblastic sarcoma: analytical review of one hundred and thirty eight cases

A rare case of acral myxoinflammatory fibroblastic sarcoma at the hand

Updates on the cytogenetics and molecular cytogenetics of benign and intermediate soft tissue tumors

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