Infectious Disease Clinics of North America volume 21, issue 4, P917-936 2007 DOI: 10.1016/j.idc.2007.08.011 View full text
|
|
Share
Jill Tolia, Leon G. Smith

Abstract: Fever of unknown origin (FUO) has fascinated and perplexed clinicians for over a century. No published guidelines exist on the approach to FUO, and studies have demonstrated that a diagnosis is never established in up to 30% of cases. A comprehensive history and physical examination are the keys to establishing a diagnosis in patient with FUO. This article provides a systematic approach to the diagnosis of FUO by delineating the most important elements of a comprehensive history and physical examination.