Fever and febrile convulsions in kittens

Seizure‐related deaths in children: The expanding spectrum

“…39,45,46 Febrile seizures occur with illness or fever of ≥100.4°F in infants and children without central nervous system infection up to ages of 5-6 years. 47 Most febrile seizures occur at between 1 and 3 years, the peak age of SUDC. 36 Febrile seizures preceding SUDC parallel terminal events in SUDEP, suggesting similar mechanisms.…”

“…Similarly, young kittens develop fever leading to lethal apnea without clinical or EEG signs of convulsions. 47 However, fever has differential effects depending on age, with younger kittens dying suddenly and older kittens first showing convulsive activity, 47 consistent with mild or absent ictal clinical signs in infants compared to older children. Autopsy of young kittens' brains showed no cellular changes, suggesting not enough time had passed for histological changes to develop.…”

“…Autopsy of young kittens' brains showed no cellular changes, suggesting not enough time had passed for histological changes to develop. 47 The absence of cellular changes despite the febrile seizure-induced death suggests that if a febrile seizure caused an infant death, it could be indistinguishable from other SUIDs.…”

Seizure‐related deaths in children: The expanding spectrum

“…39,45,46 Febrile seizures occur with illness or fever of ≥100.4°F in infants and children without central nervous system infection up to ages of 5-6 years. 47 Most febrile seizures occur at between 1 and 3 years, the peak age of SUDC. 36 Febrile seizures preceding SUDC parallel terminal events in SUDEP, suggesting similar mechanisms.…”

“…Similarly, young kittens develop fever leading to lethal apnea without clinical or EEG signs of convulsions. 47 However, fever has differential effects depending on age, with younger kittens dying suddenly and older kittens first showing convulsive activity, 47 consistent with mild or absent ictal clinical signs in infants compared to older children. Autopsy of young kittens' brains showed no cellular changes, suggesting not enough time had passed for histological changes to develop.…”

“…Autopsy of young kittens' brains showed no cellular changes, suggesting not enough time had passed for histological changes to develop. 47 The absence of cellular changes despite the febrile seizure-induced death suggests that if a febrile seizure caused an infant death, it could be indistinguishable from other SUIDs.…”

Influence of Ambient Temperature on Sleep Characteristics and Autonomic Nervous Control in Healthy Infants

“…Similar findings were reported in premature 1,2 and full-term infants, 3 as well as in animal studies. 8 It was suggested that hyperthermia could lead to a transient decrease in respiratory chemoreceptor sensitivity. 10 Animals exposed to thermal challenges developed apneas in response to respiratory irritants 41 and exhibited an enhancement of the laryngeal closure reflex.…”

Experimental Febrile Convulsions in the Developing Rat: Effects on the Cholinergic System

“…Earlier histopathological results support this hypothesis. Lennox et al (1954) and Meldrum and Brierley (1973) identified Purkinje and basket cell pathology following either hypertherrnia-or chemical-induced convulsions in cats and monkeys. Meldrum and Brierley (1973) found evidence of damage in pyramidal cells in cortical layers 3 , 5, and 6.…”

Seizure‐related deaths in children: The expanding spectrum

“…39,45,46 Febrile seizures occur with illness or fever of ≥100.4°F in infants and children without central nervous system infection up to ages of 5-6 years. 47 Most febrile seizures occur at between 1 and 3 years, the peak age of SUDC. 36 Febrile seizures preceding SUDC parallel terminal events in SUDEP, suggesting similar mechanisms.…”

“…Similarly, young kittens develop fever leading to lethal apnea without clinical or EEG signs of convulsions. 47 However, fever has differential effects depending on age, with younger kittens dying suddenly and older kittens first showing convulsive activity, 47 consistent with mild or absent ictal clinical signs in infants compared to older children. Autopsy of young kittens' brains showed no cellular changes, suggesting not enough time had passed for histological changes to develop.…”

“…Autopsy of young kittens' brains showed no cellular changes, suggesting not enough time had passed for histological changes to develop. 47 The absence of cellular changes despite the febrile seizure-induced death suggests that if a febrile seizure caused an infant death, it could be indistinguishable from other SUIDs.…”

Influence of Ambient Temperature on Sleep Characteristics and Autonomic Nervous Control in Healthy Infants

“…Similar findings were reported in premature 1,2 and full-term infants, 3 as well as in animal studies. 8 It was suggested that hyperthermia could lead to a transient decrease in respiratory chemoreceptor sensitivity. 10 Animals exposed to thermal challenges developed apneas in response to respiratory irritants 41 and exhibited an enhancement of the laryngeal closure reflex.…”

Experimental Febrile Convulsions in the Developing Rat: Effects on the Cholinergic System

“…Earlier histopathological results support this hypothesis. Lennox et al (1954) and Meldrum and Brierley (1973) identified Purkinje and basket cell pathology following either hypertherrnia-or chemical-induced convulsions in cats and monkeys. Meldrum and Brierley (1973) found evidence of damage in pyramidal cells in cortical layers 3 , 5, and 6.…”

Seizure‐related deaths in children: The expanding spectrum

“…39,45,46 Febrile seizures occur with illness or fever of ≥100.4°F in infants and children without central nervous system infection up to ages of 5-6 years. 47 Most febrile seizures occur at between 1 and 3 years, the peak age of SUDC. 36 Febrile seizures preceding SUDC parallel terminal events in SUDEP, suggesting similar mechanisms.…”

“…Similarly, young kittens develop fever leading to lethal apnea without clinical or EEG signs of convulsions. 47 However, fever has differential effects depending on age, with younger kittens dying suddenly and older kittens first showing convulsive activity, 47 consistent with mild or absent ictal clinical signs in infants compared to older children. Autopsy of young kittens' brains showed no cellular changes, suggesting not enough time had passed for histological changes to develop.…”

“…Autopsy of young kittens' brains showed no cellular changes, suggesting not enough time had passed for histological changes to develop. 47 The absence of cellular changes despite the febrile seizure-induced death suggests that if a febrile seizure caused an infant death, it could be indistinguishable from other SUIDs.…”

Influence of Ambient Temperature on Sleep Characteristics and Autonomic Nervous Control in Healthy Infants

“…Similar findings were reported in premature 1,2 and full-term infants, 3 as well as in animal studies. 8 It was suggested that hyperthermia could lead to a transient decrease in respiratory chemoreceptor sensitivity. 10 Animals exposed to thermal challenges developed apneas in response to respiratory irritants 41 and exhibited an enhancement of the laryngeal closure reflex.…”

Experimental Febrile Convulsions in the Developing Rat: Effects on the Cholinergic System

“…Earlier histopathological results support this hypothesis. Lennox et al (1954) and Meldrum and Brierley (1973) identified Purkinje and basket cell pathology following either hypertherrnia-or chemical-induced convulsions in cats and monkeys. Meldrum and Brierley (1973) found evidence of damage in pyramidal cells in cortical layers 3 , 5, and 6.…”