Feasibility study for the use of Ce3+-doped optical fibres in radiotherapy

Monès, E.; Veronese, I.; Moretti, Federico; Fasoli, M.; Loi, G.; Negri, Eva; Brambilla, Marco; Chiodini, N.; Brambilla, Gilberto; Vedda, A.

doi:10.1016/j.nima.2006.02.003

Cited by 50 publications

(27 citation statements)

References 17 publications

(21 reference statements)

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“…Ce-doped silica optical fibres proved to be an effective tool for dosimetric studies carried out with both soft X-rays [31,32] and more energetic fields used in conventional radiotherapy [33,34] and in proton therapy [35].…”

Section: Doped Silica Optical Fibre Based Dosimetersmentioning

confidence: 99%

Rare Earth Doped Silica Optical Fibre Sensors for Dosimetry in Medical and Technical Applications

2014

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Radioluminescence optical fibre sensors are gaining importance since these devices are promising in several applications like high energy physics, particle tracking, real-time monitoring of radiation beams, and radioactive waste. Silica optical fibres play an important role thanks to their high radiation hardness. Moreover, rare earths may be incorporated to optimise the scintillation properties (emission spectrum, decay time) according to the particular application. This makes doped silica optical fibres a very versatile tool for the detection of ionizing radiation in many contexts. Among the fields of application of optical fibre sensors, radiation therapy represents a driving force for the research and development of new devices. In this review the recent progresses in the development of rare earth doped silica fibres for dosimetry in the medical field are described. After a general description of advantages and challenges for the use of optical fibre based dosimeter during radiation therapy treatment and diagnostic irradiations, the features of the incorporation of rare earths in the silica matrix in order to prepare radioluminescent optical fibre sensors are presented and discussed. In the last part of this paper, recent results obtained by using cerium, europium, and ytterbium doped silica optical fibres in radiation therapy applications are reviewed.

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Section: Doped Silica Optical Fibre Based Dosimetersmentioning

confidence: 99%

Rare Earth Doped Silica Optical Fibre Sensors for Dosimetry in Medical and Technical Applications

2014

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“…In this contest, scintillating optical fiber dosimeters could be particularly useful in various applications [10][11][12][13][14][15][16] . Essentially, such dosimeter consists in a small scintillator that originates a radioluminescent (RL) signal when exposed to ionizing radiation.…”

Section: Introductionmentioning

confidence: 99%

Characterization of Yb-doped silica optical fiber as real-time dosimeter

Veronese

Chiodini

Cialdi

et al. 2017

Hard X-Ray, Gamma-Ray, and Neutron Detector Physics XIX

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The near-infrared radioluminescence and dosimetric properties of Yb-doped silica optical fibers, coupled with an optical detector prototype based on an avalanche photo-diode, were studied by irradiating the fibers with clinical beams generated by a Varian Trilogy accelerator. The performances of the system in standard and small field sizes have been also investigated comparing the output factor, percent depth dose and off axis ratio measurements of the prototypal dosimetric system with other commercial sensors.The results demonstrated that the drawback due to the stem effect in Yb-doped silica optical fibers can be managed in a simple but effective way by optical filtering. These features, together with the accuracy and precision achieved by Ybdoped fibers in relative dose assessments make the device promising for in-vivo dosimetry studies in radiation therapy.

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“…In this paper, we propose a novel type of glass composite fiber dosimeter based on the RL emission of a small portion of glass fiber doped with Cerium. Previous investigations already demonstrated the interesting RL properties of these composite fibers [19][20][21][22][23][24][25][26][27][28][29][30][31][32][33][34][35]. Moreover, with the aim to better separate the Cherenkov emission from the scintillating signal [36,37] an alternative Eu doped fiber was produced, tested and compared with Ce-doped ones.…”

Section: Introductionmentioning

confidence: 99%

Ce-doped SiO 2 optical fibers for remote radiation sensing and measurement

Chiodini

Vedda

Fasoli

et al. 2009

Fiber Optic Sensors and Applications VI

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Scintillating materials, able to convert energy of ionizing radiation into light in the visible-UV interval, are presently used in a wide class of applications such as medical imaging, industrial inspection, security controls and high energy physics detectors.In the last few years we studied and developed a new radiation sensor based on silica-glass fiber-optic technology. In its simplest configuration such device is composed by a short portion (about 10 mm) of scintillating fiber coupled to a photomultiplier through a suitably long passive silica fiber. In this work, we present new results concerning the characterization of silica based Ce and Eu doped fibers glasses obtained by a modified sol-gel method and drawn by a conventional drawing tower for optical fibers. The radioluminescence of Eu doped fibers is rather weak; moreover it displays a marked sensitivity increase during subsequent irradiations, preventing the use of such fibers in dosimetry. On the other hand Ce-doped fibers show very high radiation hardness, signal stability and reproducibility, and high sensitivity to radiations with energies from 10 keV to several tens of MeV. Numerous tests with photons (X and gamma rays), electrons, and protons have already been successfully performed. At the early stage of its market introduction it is the smallest radiation sensor, also compared to MOSFET and diode technology and it appears to be the ideal choice for in vivo measurements in medical field or remote sensing.

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Feasibility study for the use of Ce3+-doped optical fibres in radiotherapy

Cited by 50 publications

References 17 publications

Rare Earth Doped Silica Optical Fibre Sensors for Dosimetry in Medical and Technical Applications

Rare Earth Doped Silica Optical Fibre Sensors for Dosimetry in Medical and Technical Applications

Characterization of Yb-doped silica optical fiber as real-time dosimeter

Ce-doped SiO 2 optical fibers for remote radiation sensing and measurement

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