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“…Immune complexes can be formed in various ways, including idiotypic interactions [20]. Many RF only bind to lgG which is changed in one of several different ways, e.g.…”
Section: Discussionmentioning
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“…Immune complexes can be formed in various ways, including idiotypic interactions [20]. Many RF only bind to lgG which is changed in one of several different ways, e.g.…”
Section: Discussionmentioning
“…The existence of Fc receptors for all known murine Ig classes on various cell types has been demonstrated, including IgM [28-311. Complexes between IgGl (antiidiotope) and IgM (Id) were found to have an affinity for splenic lymphocytes [29]. The isotype of anti-Id antibodies, albeit of xenogeneic origin, had a profound influence on the direction of Id modulation: augmentative vs. suppressive [32].…”
Section: Possible Influences Of Ig Class or Subclass (Fc) Pieces On Tmentioning