Fatty pancreas and increased body mass index are risk factors of pancreatic fistula after pancreaticoduodenectomy

Gaujoux, Sébastien; Cortes, Alexandre; Couvelard, Anne; Noullet, S.; Clavel, Laurent; Rebours, Vinciane; Lévy, Philippe; Sauvanet, Alain; Ruszniewski, Philippe; Belghiti, Jacques

doi:10.1016/j.surg.2009.12.005

Cited by 321 publications

(309 citation statements)

References 40 publications

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“…Postoperative pancreatic fistula predicted by the models was defined by the International Study Group for Pancreatic Fistula. One studies described the development of a predictive model for POPF, based on perioperative risk factors [10]. Three studies derived a predictive model for POPF based on preoperative risk factors [8,13,17].…”

Section: Resultsmentioning

confidence: 99%

“…In terms of geography, three articles were from Asia [8,17,18] and four articles were from Europe [10][11][12][13].…”

Section: Resultsmentioning

confidence: 99%

“…Five studies reported the number of events on postoperative pancreatic fistula grades based on ISGPF [5,8,11,12,18], the medium number of events on grade A 47 (IQR 6 to 76), grade B 17 (IQR 10 to 94), and grade C 8 (IQR 5 to 25). Two studies did not report the number of events on postoperative pancreatic fistula grades [10,17].…”

Section: Number Of Patients and Postoperative Pancreatic Fistulamentioning

confidence: 99%

“…Three risk prediction models (43 %) were developed in which the number of events per variable was <10 [10,12,13]. Overall, the medium number of events per variable was 10 (IQR 7 to 39, range 5 to 175).…”

Section: Sample Sizementioning

confidence: 99%

“…Many risk factors for POPF have been identified, such as gender [8], body mass index (BMI) [9,10], status of the pancreatic parenchyma [11], diameter of the main pancreatic duct (MPD) [12], and kind of disease [13]. These risk factors lead to use some special techniques or perioperative precautions to minimize POPF rates [5,14,15].…”

Section: Introductionmentioning

confidence: 99%

See 4 more Smart Citations

Developing Risk Prediction Models for Postoperative Pancreatic Fistula: a Systematic Review of Methodology and Reporting Quality

Zhang

Guo

et al. 2016

Indian J Surg

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Postoperative pancreatic fistula is still a major complication after pancreatic surgery, despite improvements of surgical technique and perioperative management. We sought to systematically review and critically access the conduct and reporting of methods used to develop risk prediction models for predicting postoperative pancreatic fistula. We conducted a systematic search of PubMed and EMBASE databases to identify articles published before January 1, 2015, which described the development of models to predict the risk of postoperative pancreatic fistula. We extracted information of developing a prediction model including study design, sample size and number of events, definition of postoperative pancreatic fistula, risk predictor selection, missing data, modelbuilding strategies, and model performance. Seven studies of developing seven risk prediction models were included. In three studies (42 %), the number of events per variable was less than 10. The number of candidate risk predictors ranged from 9 to 32. Five studies (71 %) reported using univariate screening, which was not recommended in building a multivariate model, to reduce the number of risk predictors. Six risk prediction models (86 %) were developed by categorizing all continuous risk predictors. The treatment and handling of missing data were not mentioned in all studies. We found use of inappropriate methods that could endanger the development of model, including univariate pre-screening of variables, categorization of continuous risk predictors, and model validation. The use of inappropriate methods affects the reliability and the accuracy of the probability estimates of predicting postoperative pancreatic fistula.

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Section: Resultsmentioning

confidence: 99%

“…In terms of geography, three articles were from Asia [8,17,18] and four articles were from Europe [10][11][12][13].…”

Section: Resultsmentioning

confidence: 99%