Fatty acid, tocopherol composition and the antioxidant activity of the lipid extract from the sorghum grains growing in Algeria

Hadbaoui, Zineb; Djeridane, Amar; Yousfi, Mohamed; Saidi, Mouldi; Nadjemi, B.

doi:10.3233/s12349-010-0018-7

Cited by 12 publications

(2 citation statements)

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“…In particular the presence of unsaturated fatty acid can at least in part explain this result. For example, the phosphomolybdenum activity of lipid extract of Sorghum seeds ranged from 0.13 to 0.21 µmol VEEAC (equivalent of vitamin E)/g in another study performed by Hadbaoui et al [ 43 ]. In addition, Benalia et al [ 44 ] reported that the total antioxidant abilities of pumpkin seed oils varied from 18.88 to 56.30 mg/mL (EC 50 values).…”

Section: Resultsmentioning

confidence: 99%

Novel Signposts on the Road from Natural Sources to Pharmaceutical Applications: A Combinative Approach between LC-DAD-MS and Offline LC-NMR for the Biochemical Characterization of Two Hypericum Species (H. montbretii and H. origanifolium)

Sut

Dall’Acqua

Zengin

et al. 2023

Plants

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The members of the genus Hypericum have great potential to develop functional uses in nutraceutical and pharmaceutical applications. With this in mind, we aimed to determine the chemical profiling and biological properties of different extracts (ethyl acetate, methanol and water) from two Hypericum species (H. montbretii and H. origanifolium). We combined two approaches (LC-DAD-MS and LC-NMR) to identify and quantify chemical compounds of the extracts. Antioxidant properties (free radical quenching, reducing power and metal chelating) and enzyme inhibitory effects (cholinesterase, tyrosinase, amylase and glucosidase) were determined as biological properties. The tested extracts were rich in caffeic acid derivatives and flavonoids, and among them, 3-caffeoyl quinic acid and myricetin-3-O-rhamnoside were found to be the main compounds. The total phenolic and flavonoid levels were determined to be 50.97–134.99 mg GAE/g and 9.87–82.63 mg RE/g, respectively. With the exception of metal chelating, the methanol and water extracts showed stronger antioxidant properties than the ethyl acetate extracts. However, different results were obtained for each enzyme inhibition assay, and in general, the ethyl acetate extracts present more enzyme-inhibiting properties than the water or methanol extracts. Results from chemical and biological analyses were combined using multivariate analysis, which allowed establishing relationships between composition and observed effects of the Hypericum extracts based on the extraction solvents. To gain more insights between chemical compounds and enzyme-inhibiting effects, we performed molecular docking analysis. We observed favorable interactions between certain compounds and the tested enzymes during our analysis, confirming the data obtained from the multivariate approach. In conclusion, the obtained results may shed light on the road from natural sources to functional applications, and the tested Hypericum species may be considered potential raw materials, with promising chemical constituents and biological activities.

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Section: Resultsmentioning

confidence: 99%

Novel Signposts on the Road from Natural Sources to Pharmaceutical Applications: A Combinative Approach between LC-DAD-MS and Offline LC-NMR for the Biochemical Characterization of Two Hypericum Species (H. montbretii and H. origanifolium)

Sut

Dall’Acqua

Zengin

et al. 2023

Plants

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“…(Fazal et al, 2011). The effect of antioxidants on DPPH radical scavenging is due to their hydrogen donating ability, which is accepted as an electron or hydrogen radical to become a stable diamagnetic molecule (Hadbaoui et al, 2010 Also, S. nemorosa exhibited considerable antioxidant, antibacterial, and inhibitory enzyme activities. In conclusion, S. nemorosa is a valuable source of natural products and could be used for preparing novel functional foods, cosmetics, and pharmaceutical ingredients.…”

Section: Introductionmentioning

confidence: 99%

Comparative Study on Antioxidant Activity of Salvia Nemorosa L. From Two Different Locations

Ghafiyehsanj

Dilmaghani

Chaparzade

et al. 2020

SBJC

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In order to investigate the antioxidant activity of Salvia nemorosa L. collected from Ahar and Urmia regions in Iran at different growth stages, aerial parts of sage after collecting were dried, and for measurement, the ability of scavenge DPPH (2,2-diphenyl-1-picryl-hydrazyl-hydrate) radical in different concentrations (0.025, 0.05, 0.07, 0.1, 0.2, 0.04 and 0.6) of methanolic extracts were prepared. The result showed that the ability to scavenge DPPH radical and amount of inhibition percent of vegetative stage leaves, flowering stage leaves, and flowers increased with increasing concentrations of methanolic extracts from 0.25 to 0.6 mg/ml. In the region of Urmia, the highest amount of DPPH inhibition there was in vegetative stage leaves, and the lowest amount of DPPH inhibition was seen in flowers. In Ahar regions, unlike the Urmia region, the highest amount of DPPH inhibition there was in flowers, but the lowest of DPPH inhibition was seen in flowering stage leaves. Also, the content of inhibition of DPPH in Ahar and Urmia regions similarly increased between two phenological stages (vegetative stage leaves, flowering stage leaves, and flowers) in 0.4 mg/ml and 0.6 mg/ml concentrations

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Pretreatment Methods for Biofuel Production from Sorghum

Veljković

Đalović

Siliveru

et al. 2020

Sorghum in the 21st Century: Food – Fodder – Feed – Fuel for a Rapidly Changing World

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Fatty acid, tocopherol composition and the antioxidant activity of the lipid extract from the sorghum grains growing in Algeria

Cited by 12 publications

References 0 publications

Novel Signposts on the Road from Natural Sources to Pharmaceutical Applications: A Combinative Approach between LC-DAD-MS and Offline LC-NMR for the Biochemical Characterization of Two Hypericum Species (H. montbretii and H. origanifolium)

Novel Signposts on the Road from Natural Sources to Pharmaceutical Applications: A Combinative Approach between LC-DAD-MS and Offline LC-NMR for the Biochemical Characterization of Two Hypericum Species (H. montbretii and H. origanifolium)

Comparative Study on Antioxidant Activity of Salvia Nemorosa L. From Two Different Locations

Pretreatment Methods for Biofuel Production from Sorghum

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