respectively. The current results revealed that more than two-third (73.33%) and the majority (93.33%) of study group patients have normal cornea in right and left eyes respectively from 1st to 7th days, and there was a statistical significant difference between control and study groups on the 7 th day in relation to corneal ulcer in right and left eyes (P = 0.001 and 0.00) respectively. Conclusion: Using eye care protocol reduced the incidence of keratitis, conjunctivitis, dry eye, and corneal ulcers in patients admitted to ICU. Recommendations: Eye care should be standardized as a basic part of nursing care provided to all critically ill patients in ICU. Emphasize the importance of assessing critically ill patient's eyelids, conjunctiva, cornea, and pupil for early detection of any eye problem. The study should be applied on large probability sample.